A Clinical Trial to study effects of two medicated oral paste Triamcinolone acetonide and Amlexanox along with oral painkiller tablet for reducing pain and improving healing in patients after surgical release of upper lip-tie

Comparative evaluation of Triamcinolone acetonide versus Amlexanox Oral Mucosal Paste as Adjuncts to Oral Dispersible Ketorolac Tromethamine for Control of Post-Operative Pain and Healing following Maxillary Labial Frenectomy using RF Electrocautery- A Randomized Controlled Clinical Trial - NIL

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2026/02/104186

Enrollment

Registered

2026-02-18

Start date

Unknown

Completion date

Unknown

Last updated

2026-03-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: Q380- Congenital malformations of lips,not elsewhere classified

Interventions

Intervention1: Triamcinolone acetonide: Triamcinolone acetonide is a synthetic glucocorticoid approved by U.S Food and Drug Administration. It is available as 0.1% w/w concentration in 7.5 grams packa

Eligibility

Inclusion criteria

Inclusion criteria: 1.Systemically healthy patients 2.Diagnosed as Papillary and Papillary Penetrating Maxillary Labial Frenal Attachment 3.Good Oral Hygiene 4.With written informed consent

Exclusion criteria

Exclusion criteria: 1.Patients with Cardiac Pacemakers 2.Paients with Metallic implants 3.History of Peptic ulcer and Gastro Intestinal Bleed 4.Patients with Diabetes Mellitus and Hypertension 5.Pregnancy and Lactation 6.Patients on Systemic Steroids nad NSAIDs 7.Patients with pre-existing systemic infection 8.Smokers

Design outcomes

Primary

Measure	Time frame
To evaluate and compare reduction in post operative pain between Group A receiving Triamcinolone Acetonide and Group B receiving Amlexanox Oral Mucosal pasteTimepoint: 6 hours, 3 days, 5 days and 7 days	—

Secondary

Measure	Time frame
To compare and assess the reduction of post operative oedema and erythema between Group A receiving Triamcinolone acetonide and Group B receiving Amlexanox Oral Mucosal pasteTimepoint: 6 hours, 3 days, 5 days and 7 days;To assess intergroup comparison of wound healing at surgical site between Group A receiving Triamcinolone Acetonide and Group B receiving Amlexanox Oral Mucosal PasteTimepoint: 6 hours, 3 days, 5 days and 7 days	—

Measure

Time frame

To compare and assess the reduction of post operative oedema and erythema between Group A receiving Triamcinolone acetonide and Group B receiving Amlexanox Oral Mucosal pasteTimepoint: 6 hours, 3 days, 5 days and 7 days;To assess intergroup comparison of wound healing at surgical site between Group A receiving Triamcinolone Acetonide and Group B receiving Amlexanox Oral Mucosal PasteTimepoint: 6 hours, 3 days, 5 days and 7 days

—

Countries

India

Contacts

Public ContactDr Prakash Pai G

K.V.G Dental College and Hospital

prakashpaipai2014@gmail.com9845156405

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Mar 14, 2026