Health Condition 1: K00-K95- Diseases of the digestive system
Conditions
Interventions
Intervention1: Injection Dexmedetomidine will be administered as a loading dose of 1 mcg/kg Intravenous.
Injection Ketamine 1 mg/kg Intravenous bolus at the start of colonoscopy .
If patient movement
Sponsors
NIL
Eligibility
Inclusion criteria
Inclusion criteria: Adult patient aged 18 to 65 years ASA physical status I , II, III Elective colonoscopy with an anticipated duration of more than 45 minutes Patients willing to provide informed consent
Exclusion criteria
Exclusion criteria: Patient refusal to participate or inability to provide consent Age under 18 years or more than 65 years ASA physical status IV or above. Pregnancy or lactation Significant cardiovascular, respiratory, hepatic, or renal impairment Known allergy to Propofol, Ketamine, Fentanyl , or Dexmedetomidine History of psychiatric illness or substance abuse Anticipated dificult airway
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Intraoperative SedationTimepoint: Intraoperative Sedation -Evaluated by the Modified Observer s Assessment of Alertness/ Sedation (MOAA/S) every 5 min during and after the procedure until a recovery score of 5 is achieved | — |
Secondary
| Measure | Time frame |
|---|---|
| 1.Recovery time 2.Intraoperative Hemodynamic parameters 3.Endoscopists Satisfaction 4.Adverse effectsTimepoint: 1. Recovery time -Time interval between the withdrawal of the endoscope to a MOAA/S score of 5. 2. Intraoperative Hemodynamic parameters - At the start of the procedure & Every 5 min during the procedure to recovery. 3. Endoscopists Satisfaction during the procedure. 4. Adverse effect-During procedure & in the recovery phase till 24 hours | — |
Countries
India
Contacts
Public ContactDr Jenil Jayeshkumar Modi
Parul Institute Of Medical Sciences and Research
Outcome results
None listed