Health Condition 1: Z682- Body mass index (BMI) 20-29, adult
Conditions
Interventions
None listed
Sponsors
Ministry of Ayush
Eligibility
Inclusion criteria
Inclusion criteria: Overweight and obese individuals of either sex in the age group of 30-49 years with BMI above 23.0kg/m and below 35.0 kg/m (WHO Asia Pacific Guideline) Individuals willing to participate voluntarily & ready to follow and abide by all study procedures
Exclusion criteria
Exclusion criteria: Individuals not eligible for basti (anarha) procedure such as those with any ano-rectal pathology (e.g. haemorrhoids, fissure or fistula), or female participants in the premenstrual phase with anticipated onset of menstruation within two weeks of enrolment Individuals with known case of diabetes who have been prescribed anti-diabetic drugs or with HbA1c levels more than 7percent Individuals with known case of hypertension or Systolic pressure more than 140 mm Hg and diastolic pressure more than 90 mm Hg with or without medication Individuals who were treated with Allopathic or Ayurvedic medicines or have had surgery for weight loss/slimming/weight gain or individuals currently participating in organized weight reduction program (1 month before study enrolment) Individuals with secondary obesity caused by endocrine disorders like PCOS, or due to medications like Corticosteroids, Antidepressants, Antipsychotics Individuals with a known history of malignancy, asthma, chronic cough, coronary heart disease, psychological problems, chronic kidney and liver disease or receiving immunosuppressive medication Individuals with history or evidence of any other condition or disease that would interfere with the study evaluation, procedures, or completion making participants unfit to recruit Individuals with a history of antibiotic treatment or pro & pre-biotic supplements (1 month before study enrolment) Female participants who are pregnant or lactating
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Gut microbiome Analysis Short-Chain Fatty Acids (SCFA) and Inflammatory profile (Interleukin-6 and lipopolysaccharide) Anthropometry (Hip & waist circumference, Waist-Hip Ratio, Neck Circumference) Skinfold thicknesses (Biceps, Triceps, Subscapular & Supra-iliac) Body Composition (Total body fat, visceral fat) Timepoint: Gut microbiome Analysis: Assessed on Days 0,17, 49, 79, 109 and 139 Short-Chain Fatty Acids (SCFA) and Inflammatory profile : Assessed on Days 0,17, 49 and 139 Anthropometry : Assessed on Days 0,17, 49, 79, 109 and 139 Skinfold thicknesses : Assessed on Days 0,17, 49, 79, 109 and 139 Body Composition: Assessed on Days 0,17, 49, 79, 109 and 139 | — |
Secondary
| Measure | Time frame |
|---|---|
| Haematological parameters (Lipid Profile, Fasting Blood Sugar and Fasting Insulin) AgnibalaTimepoint: Haematological parameters : Assessed on Days 0,17, 49 and 139 Agnibala : Assessed on Days 0,17, 49 and 139 | — |
Countries
India
Contacts
Public ContactPooja Londhe
Interaction Research School for Health Affairs, Bharati vidyapeeth (Deemed to be University)
Outcome results
None listed