Health Condition 1: D50-D89- Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
Conditions
Interventions
Intervention1: Structured, Supervised Exercise Program: Aerobic Training: Outdoor walking or stationary cycling for 30 minutes per session, 3 times per week.
Resistance Training: Exercises focused on
Sponsors
Medanta - The Medicity, Gurugram
Eligibility
Inclusion criteria
Inclusion criteria: Age between eighteen and fifty years, either gender Diagnosed with rheumatoid arthritis according to the two thousand ten ACR EULAR classification criteria Disease duration between six months and five years Active disease with DAS twenty eight ESR greater than three point one On stable standard medical treatment for rheumatoid arthritis Willing to undergo dual energy X ray absorptiometry assessment Willing to participate in a six month structured aerobic and resistance exercise program Able to comply with study procedures and follow up assessments Written
Exclusion criteria
Exclusion criteria: Presence of any other autoimmune or systemic inflammatory disorder Uncontrolled medical conditions such as cardiovascular disease diabetes hypertension dyslipidemia or hypothyroidism Current or past history of malignancy Pregnant or lactating women Contraindication to dual energy X ray absorptiometry assessment Body mass index more than thirty five Any musculoskeletal neurological or cardiopulmonary condition limiting safe participation in exercise Inability or unwillingness to comply with study protocol
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Visceral adipose tissue Subcutaneous adipose tissue Rheumatoid arthritis disease activity measured by DAS twenty eight ESRTimepoint: at baseline, 4 weeks & 8 weeks | — |
Secondary
| Measure | Time frame |
|---|---|
| Handgrip strength Functional disability assessed by health assessment questionnaire disability index Systemic inflammatory markers erythrocyte sedimentation rate & C reactive protein Body composition parameters measured by dual energy X ray absorptiometry Correlation between adipose tissue distribution & disease activityTimepoint: at baseline, 4 weeks & 8 weeks | — |
Countries
India
Contacts
Public ContactKanika Markan
Noida International University
Outcome results
None listed