Evaluation and Comparasion of pinhole surgical technique with using and without using A PRF with polynucleotide hyaluronic acid gel in the treatment of multiple adjacent gingival recession defects: A randomised controlled trial.

Comparative evaluation of pinhole surgical technique with and without A PRF immersed with polynucleotide hyaluronic acid gel in the treatment of multiple adjacent gingival recession defects: A randomised controlled trial. - NIL

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2026/02/104062

Enrollment

Registered

2026-02-17

Start date

Unknown

Completion date

Unknown

Last updated

2026-03-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K056- Periodontal disease, unspecified

Interventions

Intervention1: Pinhole Surgical Technique using A PRF immersed with polynucleotide hyaluronic acid gel: Patients with Class one or two Multiple Adjacent Gingival Recession Defects to be treated using

Eligibility

Inclusion criteria

Inclusion criteria: Systemically healthy patients Patient with healthy and stable soft tissue architecture Co-operative motivated and hygiene conscious patients Patients exhibiting bilateral Millers Class one or two MAGRD Patients with more than one mm of attached gingiva at gingival recession sites Patients who gave written consent for the procedure

Exclusion criteria

Exclusion criteria: Pregnant or lactating females Tobacco smokers Uncontrolled medical conditions precluding elective surgery Untreated periodontal conditions Patients treated with any medication known to cause gingival hyperplasia Drug and alcohol abuse In addition teeth with furcation defects non vital teeth carious teeth warranting restorations and mobility more than grade two will also be excluded

Design outcomes

Primary

Measure	Time frame
To evaluate and compare Pinhole surgical technique (PST) with and without A PRF immersed with polynucleotide hyaluronic acid gel in the treatment of Multiple adjacent gingival recession defects (MAGRD) clinically and radiographically by CBCTTimepoint: Baseline 3 and 6 months	—

Secondary

Measure	Time frame
To evaluate Probing depth (PD) Clinical attachment level (CAL) Width of keratinized gingiva (WKG) Recession depth (RD) and Mean root coverage (MRC)in MAGRD when treated with PST alone at baseline 3 and 6 months postoperatively To evaluate PD CAL WKG RD and MRC in MAGRD when treated using PST with A PRF immersed with polynucleotide hyaluronic acid gel at baseline 3 and 6 months postoperatively To compare PD CAL WKG RD and MRC in MAGRD when treated using PST with and without A PRF immersed with polynucleotide hyaluronic acid gel at baseline 3 and 6 months postoperatively To evaluate and compare Gingival thickness (GT) in MAGRD when treated using PST with and without A PRF immersed with polynucleotide hyaluronic acid gel at baseline and 6 months postoperatively by CBCTTimepoint: Baseline 3 and 6 months	—

Measure

Time frame

To evaluate Probing depth (PD) Clinical attachment level (CAL) Width of keratinized gingiva (WKG) Recession depth (RD) and Mean root coverage (MRC)in MAGRD when treated with PST alone at baseline 3 and 6 months postoperatively To evaluate PD CAL WKG RD and MRC in MAGRD when treated using PST with A PRF immersed with polynucleotide hyaluronic acid gel at baseline 3 and 6 months postoperatively To compare PD CAL WKG RD and MRC in MAGRD when treated using PST with and without A PRF immersed with polynucleotide hyaluronic acid gel at baseline 3 and 6 months postoperatively To evaluate and compare Gingival thickness (GT) in MAGRD when treated using PST with and without A PRF immersed with polynucleotide hyaluronic acid gel at baseline and 6 months postoperatively by CBCTTimepoint: Baseline 3 and 6 months

—

Countries

India

Contacts

Public ContactDr Rajashri Kolte

Ranjeet Deshmukh Dental College And Research Centre

drrajashrikolte@gmail.com9011071468

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Mar 14, 2026