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This study looks at two methods of setting a breathing machine during anaesthesia to find out which one keeps the lungs more open during gallbladder surgery

A study to evaluate fixed moderate PEEP versus driving pressure guided PEEP to prevent pulmonary atelectasis in patients undergoing laparoscopic cholecystectomy under general anaesthesia.

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2026/02/103988
Enrollment
50
Registered
2026-02-16
Start date
Unknown
Completion date
Unknown
Last updated
2026-03-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical

Interventions

Intervention1: driving pressure guided PEEP to patients undergoing laparoscopic cholecystectomy: Group DP: Patients (n=30) will be ventilated with driving pressure based PEEP.Lung ultrasound will be d

Sponsors

Department of Anaesthesiology Pt BD Sharma PGIMS Rohtak
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: ASA 1 and 2 patients undergoing laparoscopic cholecystectomy

Exclusion criteria

Exclusion criteria: Refusal by patient, History of COPD or asthma, History of other significant respiratory disease, History of any cardiac illness ASA grade 3 or higher, BMI more than 35 kg/m2. Significant medical disease. Any life-threatening medical complication

Design outcomes

Primary

MeasureTime frame
To measure change in lung ultrasound score (LUS) for pulmonary atelectasis in patients of laparoscopic cholecystectomy surgeries under general anaesthesia with moderate and driving pressure guided positive end expiratory pressuresTimepoint: 0min, 10min, 20min, 40min, 60min

Secondary

MeasureTime frame
The LUS score will be used to determine the amount of aeration loss.Timepoint: A basic grading system will be used to provide a score of 0-3 to each of the 12 quadrants. The lung ultrasound score (LUS) will be calculated at preoperative and post operative of all subjects. Each of the 12 quadrants was assigned a score of 0 to 3 according to a simple grading system: O - normal lung sliding with fewer than three single B lines; 1- three or more single B lines; 2-coalescent B lines; and 3 - consolidated lung. The LUS score (0-36) will be determined by summing the scores from each of the 12 quadrants, with larger values indicating more severe aeration loss.

Countries

India

Contacts

Public ContactDr Riya bose

PGIMS rohtak

Riyabose506@gmail.com8595679131

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Mar 14, 2026