Health Condition 1: K760- Fatty (change of) liver, not elsewhere classified
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1. Individuals of all genders aged 25-50 years diagnosed with Non-Alcoholic Fatty Liver Disease by a Gastroenterologist. 2. Ultrasound confirmed Grade 1-2 hepatic steatosis. 3. Body Mass Index (BMI) between 25-35 kg per m2, indicating overweight or class 1 obesity. 4. Elevated or borderline liver enzyme levels ( ALT and or or AST), ALT greater than 56 units per liter and or or AST greater than 40 units per liter. 5. Willingness to participate and provide Informed Consent.
Exclusion criteria
Exclusion criteria: 1. Alcohol intake greater than 21 units per week (men) or greater than 14 units per week (women). 2. Other liver diseases or cirrhosis 3. Uncontrolled cardiovascular, respiratory, or endocrine disorders. 4. Participants with a history of regular exercise 5. Musculoskeletal limitations preventing exercise. 6. Use of hepatotoxic or lipid-lowering medications (e.g., corticosteroids, statins) 7. Pregnancy or lactating
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 1. Hepatic steatosis assessed using ultrasonography (USG) through standardized grading of liver echogenicity. 2. Hepatic function evaluated using serum liver enzyme levels (ALT and AST) obtained through laboratory blood tests.Timepoint: 1. Hepatic steatosis assessed using ultrasonography (USG) through standardized grading of liver echogenicity at baseline and end of 8 weeks. 2. Hepatic function evaluated using serum liver enzyme levels (ALT and AST) obtained through laboratory blood tests at baseline and end of 8 weeks. | — |
Secondary
| Measure | Time frame |
|---|---|
| 1. Central adiposity assessed using the waist hip ratio (WHR) measured with a non-elastic measuring tape. 2. Quality of life assessed using the Short Form-36 (SF-36) questionnaire.Timepoint: 1. Central adiposity (waist hip ratio) will be assessed pre-intervention & post-intervention, at baseline & end of 8 weeks. 2. Quality of life (SF-36) will be assessed pre-intervention & post-intervention, at baseline & end of 8 weeks. | — |
Countries
India
Contacts
KAHER Institute of Physiotherapy, Belagavi