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Comparison of effects of general anaesthesia on heart in premenopausal and postmenopausal women

Comparison of Perioperative Cardiovascular Responses to General Anaesthesia in Premenopausal and Postmenopausal Women undergoing general anaesthesia: A Prospective Observational pilot Study - NIL

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
CTRI
Registry ID
CTRI/2026/02/103964
Enrollment
50
Registered
2026-02-16
Start date
Unknown
Completion date
Unknown
Last updated
2026-03-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical

Interventions

Intervention1: Nil: Nil

Sponsors

Self
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Female patients aged 18 to 75 years Undergoing general anaesthesia ASA physical status I and II

Exclusion criteria

Exclusion criteria: Known cardiovascular disease (ischemic heart disease, heart failure, arrhythmias) Uncontrolled Hypertension Diabetes mellitus with autonomic neuropathy Hormone replacement therapy BMI >30 kg/m Emergency surgery

Design outcomes

Primary

MeasureTime frame
To compare mean arterial pressure (MAP) changes between premenopausal and postmenopausal women during induction.Timepoint: Immediately after induction of general anaesthesia—

Secondary

MeasureTime frame
1. To compare mean arterial pressure (MAP) changes between premenopausal & postmenopausal women during intubation, & maintenance of anaesthesia 2. To compare heart rate (HR) changes between premenopausal & postmenopausal women during induction, intubation, & maintenance of anaesthesia 3. To evaluate differences in heart rate variability (HRV) parameters between the two groups during induction, intubation, & maintenance of anaesthesia 4. To compare vasopressor requirements between premenopausal & postmenopausal women Timepoint: Baseline, 1 minute after intubation with endotracheal tube & once in every 15 minutes in the intraoperative period—

Countries

India

Contacts

Public ContactA Chaitanya Pratyusha

All India Institute of Medical Sciences, Bibinagar

chaitanyapa9@gmail.com9063571725

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Mar 14, 2026