Study on adults with Knee Osteoarthritis to compare the effect of two Ayurvedic medicated ghees, Sarvamayantaka Ghrita and Guggulutiktaka Ghrita, given through enema and oral intake, on symptoms and daily movement ability.

AN OPEN LABEL RANDOMIZED COMPARATIVE CLINICAL STUDY TO EVALUATE THE COMBINED EFFICACY OF MATRA BASTI AND SHAMANA SNEHAPANA WITH SARVAMAYANTAKA GHRITA OVER GUGGULUTIKTAKA GHRITA IN JANU SANDHIGATA VATA vis- -vis KNEE OSTEOARTHRITIS - NIL

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2026/02/103950

Enrollment

Registered

2026-02-16

Start date

Unknown

Completion date

Unknown

Last updated

2026-03-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: M179- Osteoarthritis of knee, unspecified

Interventions

None listed

Eligibility

Inclusion criteria

Inclusion criteria: 1. Subjects fulfilling the diagnostic criteria. 2. Subjects of either gender, aged between 30-70 years, irrespective of socio-economic status. 3. Subjects willing to provide informed consent for the study.

Exclusion criteria

Exclusion criteria: 1. Subjects with Infections, Neoplasms, Congenital diseases of the Knee Joint, Rheumatoid arthritis, Psoriatic arthritis and Gouty arthritis. 2. Subjects with a history of injury (less than 3 months) and any fractures of the Knee Joint. 3. Pregnant and lactating women.

Design outcomes

Primary

Measure	Time frame
Change in WOMAC score. Timepoint: Day 0, before treatment Day 10, after Matra Basti Day 40, after completion of treatment	—

Secondary

Measure	Time frame
1. Range of Movements of Knee Joint- Flexion and Extension measured using Goniometer. 2. Reduction in Knee Joint swelling measured by girth at superior pole of patella. 3. Reduction in Crepitus. 4. Reduction in Tenderness.Timepoint: Day 0, before treatment Day 10, after Matra Basti Day 40, after completion of treatment	—

Countries

India

Contacts

Public ContactDr BEENA M D

JSS Ayurveda Medical College and Hospital

drpbsreddy@yahoo.com9538367282

Outcome results