A study on the use of Nigella sativa(Black seed) solution for cleaning root canals in people with diabetes

Antimicrobial effectiveness of Nigella sativa as final root canal irrigant among patients with Type II Diabetes mellitus-A Randomized Controlled Trial - nil

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2026/02/103911

Enrollment

Registered

2026-02-16

Start date

Unknown

Completion date

Unknown

Last updated

2026-03-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: E119- Type 2 diabetes mellitus without complications

Interventions

Intervention1: Nigella sativa: Nigella sativa solution will be used as the final root canal irrigant for 5 minutes during a single root canal treatment visit in patients with Type 2 diabetes having ir

Eligibility

Inclusion criteria

Inclusion criteria: Type II Diabetic patients of irreversible pulpitis with apical periodontitis in relation to posterior molar teeth

Exclusion criteria

Exclusion criteria: Teeth with root fracture Teeth with developmental defects Teeth with calcified canal Teeth that cannot be isolated with rubber dam

Design outcomes

Primary

Measure	Time frame
Quantitative assessment of bacterial load from infected root canals of infected root canals of Type II diabetic patients with a diagnosis of irreversible pulpitis with apical periodontitis before and after the intervention in both the groupsTimepoint: 1 day	—

Secondary

Measure	Time frame
To correlate clinical signs and symptoms with bacterial load before and after the interventions in both the groupsTimepoint: 1 day	—

Countries

India

Contacts

Public ContactDr Abdul Khader Shibah

K V G Dental College and Hospital

moksha.nayak@gmail.com9448026828

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Mar 14, 2026