A study to compare three additional treatments (platelet concentrate injection, laser therapy, and hyaluronic acid gel) to improve healing and gum health in patients with chronic gum disease.

Comparative evaluation of the adjunctive effect of injectable platelet rich fibrin (i-PRF), 970 nm diode laser and hyaluronic acid on post operative healing and clinical parameters for the treatment of chronic periodontitis. - NIL

Status

Recruiting

Phases

Phase 3

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2026/02/103886

Enrollment

Registered

2026-02-16

Start date

Unknown

Completion date

Unknown

Last updated

2026-03-30

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

Intervention1: OFD: Open Flap Debridement Control Intervention1: i-PRF and OFD: Injectable Platelet Rich Fibrin (platelet concentrate) made from patients own venous blood used as an adjunct to OFD Con

Eligibility

Inclusion criteria

Inclusion criteria: Medically healthy patients. Patient who have persistent PPD equal to or more than 5 mm and CAL equal to or more than 4 mm. Patients who want to participate in the study. Patients who are capable of maintaining proper dental hygiene.

Exclusion criteria

Exclusion criteria: Patients who have uncontrolled systemic diseases. Patients who had flap surgery during the last six months. Patients who require extensive osseous manipulation. Patients who are on antibiotic and long term steroids. Tobacco chewers and smokers. Pregnant and lactating women.

Design outcomes

Primary

Measure	Time frame
Plaque Index, Gingival Index, Probing Pocket Depth, Clinical Attachment Level.Timepoint: Baseline and 1 month & 3 months post-surgery.	—

Secondary

Measure	Time frame
Post operative pain.Timepoint: 24 hours, 3rd day and 7th day post-surgery.;Post operative healing.Timepoint: 24 hours, 3rd day and 7th day post-surgery.	—

Countries

India

Contacts

Public ContactDr Vivek Srivastava

Sardar Patel Post Graduate Institute of Dental and Medical Sciences

drviveksrivastav89@gmail.com9936859555

Outcome results