Health Condition 1: O- Medical and Surgical
Conditions
Interventions
Intervention1: Injection dexmedetomidine plus ketamine infusion: patients will a receive loading dose of injection dexmedetomidine (drug 1) 0.5mcg/kg and injection ketamine (drug
2) 0.3 mg/kg, slowly
Sponsors
Pandit B.D Sharma PGIMS Rohtak
Eligibility
Inclusion criteria
Inclusion criteria: Adult patients age 18 to 65 years of either sex belonging to ASA physical status 1/2 scheduled for infra umbilical abdominal surgery under subarachnoid block
Exclusion criteria
Exclusion criteria: Refusal to participate. Contraindication to spinal anaesthesia Ischemic heart disease recent head injury or neuro psychiatric illness Known allergy to the drugs being used Pregnancy Surgery duration, less than one hour
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| To study the effect of dexmedetomidine plus ketamine infusion on duration of analgesia, post-operative pain score and rescue analgesia requirementTimepoint: 0mins, 5mins , 10mins , 15mins , 20mins , 25mins , 30mins , 40mins, 50mins,60mins, 70mins , 80mins, 90mins, 100mins , 110mins , 120mins, in post operative period | — |
Secondary
| Measure | Time frame |
|---|---|
| Changes in haemodynamic parameters.Timepoint: 30mins , 1hr, 2hr, 6hrs, 12hrs , 24hrs;Ramsay sedation scoresTimepoint: 15mins , 30mins , 45mins ,60mins, 75mins , 90mins , 105mins , 120mins, 135mins, 150mins, in post operative period;Patient satisfactionTimepoint: 24hrs post operative period;Complications, if any: Hypotension, Bradycardia, Shivering, Nausea and vomiting, hallucinations, Nightmares/vivid dreams, visual disturbances (nystagmus, blurred vision)Timepoint: At any given point of time in post operative period till 24hrs | — |
Countries
India
Contacts
Public ContactDr Sanjiv Kumar
PGI Rohtak
Outcome results
None listed