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Effect of Antioxidant Therapy on Semen Quality in Men With Infertility Related to Oxidative Stress.

A prospective interventional study assessing oxidative stress levels in sub fertile males and the impact of antioxidant therapy on semen parameters - NIL

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2026/02/103715
Enrollment
30
Registered
2026-02-12
Start date
Unknown
Completion date
Unknown
Last updated
2026-03-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: N469- Male infertility, unspecified

Interventions

Intervention1: Antioxidant Therapy: Oral antioxidant supplementation (combination of Vitamin C , Vitamin E , Zinc , Selenium and coenzyme Q10) administrated daily for three months. Control Interventio

Sponsors

Saveetha Institute of Medical and Technical sciences (SIMATS)
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Male patients aged 18-45 years with primary or secondary infertility , abnormal semen parameters ,and evidence of oxidative stress, willing to participate and provide informed consent.

Exclusion criteria

Exclusion criteria: Azoospermia genetic causes of infertility active genital infections chronic systemic illness history of chemotherapy or radiotherapy substance abuse

Design outcomes

Primary

MeasureTime frame
Change in semen parameter sperm concentration, motility and morphology before and after antioxidant therapyTimepoint: Baseline and 12 weeks after initiation of antioxidants—

Secondary

MeasureTime frame
NILTimepoint: NIL—

Countries

India

Contacts

Public ContactDr Nidhi Sharma S

Saveetha Institute of Medical and Technical science

nidhisharma.smc@saveetha.com9445560392

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Mar 14, 2026