None listed
Conditions
Interventions
Intervention1: Group 3: MINST along with HA: Group 3 is Test group 2 in which after completion of MINST, 24% EDTA gel would be applied on the root surface of the involved tooth for 2 min. The site wou
Sponsors
Sudha Rustagi College of Dental Sciences
Eligibility
Inclusion criteria
Inclusion criteria: -Males and females aged more than or equal to 18 years. Patients with untreated severe or advanced periodontitis, that is, stage III or IV with slow or moderate rate of progression that is, grade A or B Presence of interdental periodontal defects with PD more than or equal to 5 mm associated with an intrabony component more than or equal to 2 mm at single rooted teeth or at molars with less than or equal to class I furcation involvement. One intrabony defect would be treated per patient. If multiple teeth presented pockets associated with an intrabony defect, only the site with the deepest PD would be selected for the study. In case of same PD in two or more intrabony defects per patient, the site with the deepest radiographic intrabony component would be selected. Patients with at least 10 teeth per arch.
Exclusion criteria
Exclusion criteria: -Patients with systemic diseases. -Pregnant or lactating females. -Tobacco smokers (more than or equal to 10 cigarettes per day). -Multi-rooted teeth with class II and class III furcation defects. -Third molars. -Teeth with grade III mobility. -Peri-apical pathology and acute abscess. -Patients without adequate level of oral hygiene -following step 1 of periodontal therapy (full-mouth plaque score [FMPS] of more than 20%). -Prolonged antibiotic treatment or anti-inflammatory treatment within 6 months prior to periodontal therapy -Non-surgical periodontal treatment in the past 6 months, or surgical periodontal treatment in the past 12 months -History of radiation therapy in the head and neck region -Presence of subgingival restoration which could interfere with clinical measurements
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| To assess and compare Probing Depth, Clinical Attachment Level, Radiographic defect fill and Radiographic defect angle before and after the treatment with MINST as a monotherapy, MINST in combination with EMD and MINST along with hyaluronic acid in treatment of patients with intrabony defects.Timepoint: post- intervention 3rd and 6th month | — |
Secondary
| Measure | Time frame |
|---|---|
| To assess and compare full mouth plaque score (FMPS), full mouth bleeding score (FMBS), gingival recession (measured from the CEJ to the gingival margin) in all the three groups i.e MINST as a monotherapy, MINST in combination with EMD and MINST along with hyaluronic acid in treatment of patients with intrabony defects.Timepoint: post- intervention 3rd and 6th month | — |
Countries
India
Contacts
Public ContactDr Shivam Khanna
Sudha Rustagi College of Dental Sciences and Research
Outcome results
None listed