Comparison between Shiv mix and propofol versus Dexmedetomidine and propofol for patients who are posted for the repair of tympanic membrane who are having perforation of tympanic membrane. This study will be using sedation through out surgery.

Comparison of Shiv mix and propofol versus Dexmedetomidine and propofol in patients posted for Tympanoplasty surgeries. - NIL

Status

Recruiting

Phases

Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2026/02/103644

Enrollment

200

Registered

2026-02-11

Start date

Unknown

Completion date

Unknown

Last updated

2026-03-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: - Health Condition 2: -

Interventions

Intervention1: In one group of patients we will be using Shiv mix and propofol for sedation of patients. In other group of patients we will be using Dexmedetomidine and propofol for sedation of patien

Eligibility

Inclusion criteria

Inclusion criteria: 200 patients of AsA grade I and II between the age groups of 18-60 years.

Exclusion criteria

Exclusion criteria: Patients refusal to give consent, Patients for whom any component of mixture is containdicated, History or family history of malignant hyperthermia, ASA physical status of III or higher will be excluded, Patients having history of convulsions, meningitis, infections, anaemia (Hb less than 9 gm %), Patients having known hepatic, renal or neuromascular diseases, Patients having known respiratory system diseases.

Design outcomes

Primary

Measure	Time frame
Haemodynamic stability of patients, analgesia and satisfaction level of patients assessed throughout surgery and in post-operative period.Timepoint: Haemodynamic stability of patients, analgesia, satisfaction of patients assessed post-operatively.	—

Secondary

Measure	Time frame
NILTimepoint: NIL	—

Countries

India

Contacts

Public ContactDr Yogita Sorte

Peoples College of Medical Sciences and Research Centre

yogitanimje84@gmail.com9806179234

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Mar 14, 2026