Effect of laser activation on LI4 (Hegu) point for the patients undergoing root canal treatment

Effect of laser activation of LI4 (Hegu) point on the inferior alveolar nerve block for mandibular molars with symptomatic irreversible pulpitis a randomised controlled clinical trial - NIL

Status

Recruiting

Phases

Phase 1Phase 2

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2026/02/103603

Enrollment

Registered

2026-02-11

Start date

Unknown

Completion date

Unknown

Last updated

2026-09-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K040- Pulpitis

Interventions

Intervention1: LOW LEVEL LASER ACTIVATION: Low level laser activation on LI4 point with Diode laser with following parameters: Power output 0.2 to 1 W, Wavelength 660nm, Energy 4J, non-contact mode 2-

Eligibility

Inclusion criteria

Inclusion criteria: Patients with mild or no systemic diseases according to ASA physical status classification (Class 1 and 2). The patient with moderate to severe (more than or equal to 66) pain prior to the procedure scored using a visual analog scale. Patient diagnosed with symptomatic irreversible pulpitis in mandibular first or second molar that will be confirmed with cold test and electric pulp testing. Radiographic confirmation of caries involving pulp and devoid of any periapical changes. History of spontaneous pain or nocturnal pain.

Exclusion criteria

Exclusion criteria: Patients who had taken any analgesics or systemic steroids in the past 24 hours at the time of intervention. Patients allergic to local anesthetic or other NSAIDS. Patients under opioids, antidepressants and other medications for mental disorders. Pregnant & breast-feeding women. History of gastrointestinal tract related disease, metabolic and hormonal disorders. Teeth with periodontal disease, non-restorable tooth structure loss, and radiographic observations like break in lamina dura and periapical radiolucency. Patients with history of any other painful orofacial diseases.

Design outcomes

Primary

Measure	Time frame
Success of IANB will be assessed using VAS scores (subjective measure) and the scores given by blinded observers in SEM scale (objective measure).Timepoint: One time assessment of pain score immediately after the procedure.	—

Secondary

Measure	Time frame
Pulse rate, respiratory rate & SpO2 values.Timepoint: Assessment of Pulse rate, respiratory rate & SpO2 values during the procedure & immediately after the procedure.	—

Countries

India

Contacts

Public ContactSankar Vishwanath

KSR Institute of Dental science and Research

sankaravg@ksridsr.edu.in9042050014

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Sep 19, 2026