Health Condition 1: O- Medical and Surgical
Conditions
Interventions
Intervention1: Intravenous Nalbuphine as a premedication.: To evaluate the efficacy of the drug when used as a premedication for general anaesthesia in attenuating the hemodynamic response (blood pres
Sponsors
College of Medicine and Sagore Dutta Hospital
Eligibility
Inclusion criteria
Inclusion criteria: 1. Patients undergoing elective laparoscopic cholecystectomy under general anaesthesia. 2. Patients who have given written informed consent to participate in the study. 3. Patients with ASA (American Society of Anaesthesiologist) grade I and II
Exclusion criteria
Exclusion criteria: 1.Patienst with ASA grade III and IV 2.Patients refusal for participation in study 3.Patients with hepatic, renal or cardiopulmonary abnormality 4.Patients with uncontrolled hypertension and diabetes mellitus 5.Patients with psychiatric illness 6.Patients with hypersensitivity to any of the research drugs.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| To compare systolic blood pressure, diastolic blood pressure and mean arterial pressure changes during laryngoscopy between the two drugs.Timepoint: Systolic blood pressure, diastolic blood pressure and mean arterial pressure will be recorded at baseline, after giving study drug, immediately after laryngoscopy and intubation, 1st, 3rd, 5th, 7th 10th, and 15th minutes after intubation. | — |
Secondary
| Measure | Time frame |
|---|---|
| To compare heart rate changes during laryngoscopy between the two drugs.Timepoint: Heart rate will be recorded at baseline, after giving study drug, immediately after laryngoscopy and intubation, 1st, 3rd, 5th, 7th 10th, and 15th minutes after intubation.;To compare the side effects of the two adjuvants used(if any).Timepoint: Intraoperative and postoperative period. | — |
Countries
India
Contacts
Public ContactDr Nairita Mayur
College of Medicine and Sagore Dutta Hospital
Outcome results
None listed