Health Condition 1: M179- Osteoarthritis of knee, unspecified
Conditions
Interventions
Intervention1: inj kanacort: 2 ml intraarticular knee injection one time injection 15 min for injection
Control Intervention1: platelet reach plasma: 5 ml intraarticular knee injection of platelet rea
Sponsors
GMERS MEDICAL COLLEGE AND HOSPITAL
Eligibility
Inclusion criteria
Inclusion criteria: Patients diagnosed with Knee Osteoarthritis Grade 1 and 2 (Kellgren Lawrence grading) at the OPD of Orthopaedics department of GMERS HOSPITAL,GOTRI and are comparable with respect to Age between 40 to 60 years with unilateral knee pain(OA) Age between 40 to 60 years with bilateral knee pain with severe pain in one knee(OA) Body mass index Pre-injection WOMAC SCORE,VAS SCALE, & KOOS SCORE.
Exclusion criteria
Exclusion criteria: Immunosuppressed patients Patients with secondary osteoarthritis Patients with inflammatory disorder of joints(RA) Patients who have received any intraarticular injections within past 6 months Patients with K/C/O diabetes Patients with tumours, metabolic diseases of bone Patients who underwent knee arthroscopy in last 6 months
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 1 week,6 weeks,3 months, and 6 monthsTimepoint: 1 week,6 weeks,3 months, and 6 months | — |
Secondary
| Measure | Time frame |
|---|---|
| Secondary outcomes included improvement in knee function, reduction in stiffness, and enhancement of quality of life as assessed by validated scoring systems such as WOMAC and VAS. PRP injections demonstrated superior long-term improvement in functional scores and sustained pain reduction compared to corticosteroid injections. Corticosteroids showed earlier symptomatic relief, but effects diminished over time. No major adverse events were reported in either group, indicating both treatments were safe and well tolerated.Timepoint: Based on WOMAC, VAS and KOOS score Scoring System criteria at 1 week,6 weeks,3 months, and 6 months | — |
Countries
India
Contacts
Public ContactBHUMIL CHAMPAKBHAI RATHOD
GMERS MEDICAL COLLEGE AND HOSPITAL VADODARA
Outcome results
None listed