Study whether Injection Dexamethasone prolongs the duration of spinal anaesthesia and decreases post-operative pain in caesarean section patients

Effect of IV dexamethasone on the duration of spinal anesthesia administered with 0.5% hyperbaric bupivacaine and morphine in elective lower segment caesarean section Double-blind randomized controlled trial - NIL

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2026/02/103585

Enrollment

Registered

2026-02-10

Start date

Unknown

Completion date

Unknown

Last updated

2026-03-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O00-O9A- Pregnancy, childbirth and the puerperium

Interventions

Intervention1: IV Dexamethasone injection 2ml which has 8 mg immediately after child birth: After the pre-anesthetic assessment, patients who are included in the study are randomized into two groups f

Eligibility

Inclusion criteria

Inclusion criteria: 1. Category : Term Pregnant females 2. Age : 21 - 40 years 3. ASA PS : Grade II 4. Patients undergoing elective LSCS under spinal anaesthesia. 5. Patients who have given valid informed consent. 6. Patients who are able to rate their pain with good GCS and Normal mental status

Exclusion criteria

Exclusion criteria: 1. Patient refusal 2. Patients with severe hypovolemia or hemodynamically unstable 3. Patients with Bleeding Diathesis or coagulation abnormalities 4. Severe pre-eclampsia 5. Eclampsia 6. Gestational diabetes mellitus 7. Ht less than 140cm or more than 180cm 8. BMI more than 30 9. Fetal distress 10. Cord prolapse 11. Infection at the probable site of Spinal anaesthesia 12. Spine deformity 13. Active labour 14. Sepsis 15. Cardiac or neurological disease 16. Failed spinal changed to GA 17. History of Allergy to Dexamethasone

Design outcomes

Primary

Measure	Time frame
VAS SCORETimepoint: immediately post operatively and then at 15 min intervals till 4 hours and at 5, 6, 12, 24 hours post-operatively	—

Secondary

Measure	Time frame
1. Assessing duration of sensory block using pinprick 2. Assessing duration of motor block duration using Modified Bromage Scale grading 3. Hemodynamic parametersTimepoint: at 15 min intervals till 4 hours and at 5th and 6th hour post-operatively;4. Incidence of PONV (post operative nausea and vomiting) 5. Incidence of post-operative shivering 6. Incidence of complicationsTimepoint: Post operatively if present;7.Rescue post-operative analgesiaTimepoint: Post operatively the first time patient feels pain;8. Total administered analgesicsTimepoint: At the end of 24 hrs post operatively	—

Measure

Time frame

1. Assessing duration of sensory block using pinprick 2. Assessing duration of motor block duration using Modified Bromage Scale grading 3. Hemodynamic parametersTimepoint: at 15 min intervals till 4 hours and at 5th and 6th hour post-operatively;4. Incidence of PONV (post operative nausea and vomiting) 5. Incidence of post-operative shivering 6. Incidence of complicationsTimepoint: Post operatively if present;7.Rescue post-operative analgesiaTimepoint: Post operatively the first time patient feels pain;8. Total administered analgesicsTimepoint: At the end of 24 hrs post operatively

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Countries

India

Contacts

Public ContactDr Anusha B

Mehta Multispeciality Hospital, CHETPET, CHENNAI

headanaesthesia@mehtahospital.com9884739206

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Mar 14, 2026