It is the study of comparison between intrathecal Bupivacaine with Clonidine versus intrathecal Bupivacaine with Dexmedetomidine in patients having Severe Pre-eclampsia posted for lower segment caesarean section surgeries.

Comparison of Clonidine versus Dexmedetomidine as an adjuvant to Bupivacaine for patients having Severe Pre-eclampsia posted for lower segment caesarean section surgeries. - NIL

Status

Recruiting

Phases

Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2026/02/103557

Enrollment

100

Registered

2026-02-10

Start date

Unknown

Completion date

Unknown

Last updated

2026-03-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: -

Interventions

Intervention1: The Selection of Patients will be carried out on the basis of even and odd IPD numbers: An initial preoperative counselling and reassurance to again confidence of the patient will be do

Eligibility

Inclusion criteria

Inclusion criteria: 1. Patients belonging to ASA grade II and III posted for caesarean surgery having severe pre-eclampsia posted for lower segment caesarean section surgeries. 2. Patients between the age group 20-40 years.

Exclusion criteria

Exclusion criteria: 1. Patient refusal. 2. Patient having systemic cardiovascular, respiratory, hepatic, renal or central nervous system disorders. 3. Patients with haemorrhagic disorders or patients who are on anticoagulant therapy. 4. Disease and deformities of spinal cord or vertebral column. 5. Patients with hypersensitivity to study drug, patients with known allergy or hypersensitivity to local anaesthetics. 6. Patients with psychiatric illness and/or on any kind of sedative medication.

Design outcomes

Primary

Measure	Time frame
Haemodynamic stability, post operative analgesia, patient satisfaction.Timepoint: Haemodynamic stability, post operative analgesia, patient satisfaction throughout surgery and in post-operative period till patient will demand for first rescue analgesia.	—

Secondary

Measure	Time frame
NILTimepoint: NIL	—

Countries

India

Contacts

Public ContactDr Yogita Sorte

Peoples College of Medical Sciences and Research Centre

yogitanimje84@gmail.com9806179234

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Mar 14, 2026