A Study on the Effectiveness of a Siddha Herbal Medicine in Reducing Nicotine Dependence Among Smokers

Preclinical and Clinical Evaluation of Siddha Polyherbal Formulation in the management of Nicotine Dependence in Smokers - NIL

Status

Active, not recruiting

Phases

Phase 2

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2026/02/103548

Enrollment

Registered

2026-02-10

Start date

Unknown

Completion date

Unknown

Last updated

2026-03-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: F172- Nicotine dependence

Interventions

Intervention1: SIDDHA POLYHERBAL FORMULATION(SPF): 4 gms of SPF Chooranam in 160 ml of water boiled and reduced to 40 ml and given twice a day for 40 days Control Intervention1: NIL: NIL

Eligibility

Inclusion criteria

Inclusion criteria: All genders Everyday smokers Participants willing to undergo Self Assessment questionnaire from Fagerstrom Test for Nicotine Dependence(FTND) with the score smaller than 5 Participants having the serum cotinine level smaller than 25 ng per ml

Exclusion criteria

Exclusion criteria: History of stroke Myocardial infarction or Angina pectoris Arthritis Pulmonary tuberculosis Asthma Chronic Obstructive Pulmonary Disease Cancer Hepatitis Pregnant Women will be excluded from the study

Design outcomes

Primary

Measure	Time frame
To test the proportion of the study drug achieving reduction of nicotine dependence level in smokers by FTND Questionnaire methodTimepoint: 40 days	—

Secondary

Measure	Time frame
Reduction of serum cotinine level smaller than 25 ng per mlTimepoint: 40 days	—

Countries

India

Contacts

Public ContactDr J SRIDEVI

NATIONAL INSTITUTE OF SIDDHA

drmanjarimd@gmail.com8056903083

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Mar 14, 2026