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Evaluating the effects of intermittent Oxygen therapy on immature red blood cells in head and neck cancer patients

Evaluating the effects of Perioperative hyperoxic intermittent stimuli on reticulocyte levels in head and neck cancer patients: a Randomized controlled trial - NIL

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2026/02/103544
Enrollment
52
Registered
2026-02-10
Start date
Unknown
Completion date
Unknown
Last updated
2026-09-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical

Interventions

Intervention1: Normobaric Oxygen group: Intermittent, 60% oxygen will be given for 2 hours on the day before surgery and on postoperative days 1 and 3 via venturi mask. Reticulocyte count will be asse

Sponsors

AIIMS New Delhi
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: The study will include adult patients (aged 18 or older) eligible for head and neck oncological surgery.

Exclusion criteria

Exclusion criteria: 1. Severe renal insufficiency 2. Transfusion of red blood cells, plasma during the perioperative period, 3. Bleeding requiring repeated transfusions during or after surgery, 4. Severe respiratory syndrome necessitating continuous oxygen, 5. Intolerance to an oxygen mask.

Design outcomes

Primary

MeasureTime frame
Percentage change in reticulocyte count from baseline to day 4 within each group.Timepoint: 1 day before surgery and on postop day 4—

Secondary

MeasureTime frame
Hematocrit levels measured at baseline and on day 4.Timepoint: 1 day before surgery and on postop day 4;Hemoglobin levels measured at baseline and on day 4Timepoint: 1 day before surgery and on postop day 4;Neutophil-lymphocyte ratio measured at baseline and on day 4Timepoint: 1 day before surgery and on postop day 4—

Countries

India

Contacts

Public ContactDr Brajesh kumar Ratre

All India Institute Of Medical Sciences, New Delhi

brajesh.ratre@gmail.com8696156799

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Sep 19, 2026