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To study the effects of intranasal Desmopressin spray in Functional endoscopic sinus surgery (FESS)

Preoperative intranasal Desmopressin spray: Its role in the quality of surgical field and intraoperative blood loss during elective Functional endoscopic sinus surgery (FESS), A randomized controlled trial - NIL

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2026/02/103533
Enrollment
60
Registered
2026-02-10
Start date
Unknown
Completion date
Unknown
Last updated
2026-03-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical

Interventions

Intervention1: Desmopressin: 1 puff (10 microgram) of intranasal Desmopressin before 30 mins of start of surgery Control Intervention1: Normal saline: 1 puff of intranasal saline spray before 30 mins

Sponsors

Dr Drashti Patel
Lead Sponsor
Dr Suktara Sharma
Collaborator

Eligibility

Inclusion criteria

Inclusion criteria: 1. Patients with chronic rhino sinusitis required for FESS

Exclusion criteria

Exclusion criteria: 1. Bleeding disorder 2. Pregnancy 3. Cardiac disease 4. Known hypersensitivity to Desmopressin

Design outcomes

Primary

MeasureTime frame
1.Surgical field grade (Boezart score) in 0-5 scores at 15th and 60th mins after start of surgery 2.Intraoperative blood loss in mlTimepoint: After surgery complition—

Secondary

MeasureTime frame
1.Operative time in hours 2.Surgeon s satisfaction grade (Likert scale) from 1-5 scale after completion of surgery 3.Desmopressin related Intra/post operative complication 4.Hemodynamic parameters (BP and HR) at 15th and 60th mins after start of surgery 5.Post operative S. Na+ level after 1 hr and 6 hrs of surgeryTimepoint: After surgery complition—

Countries

India

Contacts

Public ContactDr Drashti Patel

GCS medical college, hospital and research centre

drashti4896@gmail.com9979849537

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Mar 14, 2026