Health Condition 1: G891- Acute pain, not elsewhere classified
Conditions
Interventions
Intervention1: Intravenous IBUPROFEN: Intravenous ibuprofen 400 mg diluted in 100 ml of normal saline administered over 30 minutes 30 minutes before the start of surgery, followed by repeat doses ever
Sponsors
Saveetha Medical College and Hospital
Eligibility
Inclusion criteria
Inclusion criteria: Patients aged 18 65 years ASA physical status I and II Patients undergoing elective abdominal surgery under general anesthesia Patients willing to give written informed consent
Exclusion criteria
Exclusion criteria: Known hypersensitivity to NSAIDs Renal impairment or peptic ulcer disease Bleeding disorders Pregnant or lactating women Chronic analgesic or opioid use Hepatic dysfunction
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Postoperative pain intensity measured using the Visual Analogue Scale (VAS) score during the first 24 hours following abdominal surgery.Timepoint: Baseline (immediately after extubation), 1 hour, 2 hours, 4 hours, 6 hours, 12 hours, and 24 hours postoperatively. | — |
Secondary
| Measure | Time frame |
|---|---|
| To evaluate the safety profiles of IV ibuprofen & IV ketorolac by assessing the incidence of adverse effects. To assess the duration of pain relief provided by IV ibuprofen compared to IV ketorolac. To analyze the impact of both medications on opioid-sparing effects in the postoperative period. To identify any differences in patient satisfaction & overall outcomes related to pain management with IV ibuprofen & IV ketorolac. Timepoint: Baseline (immediately after extubation), 1 hour, 2 hours, 4 hours, 6 hours, 12 hours, & 24 hours postoperatively. | — |
Countries
India
Contacts
Public ContactDr Bharathi
Saveetha Medical College and Hospital
Outcome results
None listed