Health Condition 1: O- Medical and Surgical
Conditions
Interventions
Intervention1: DEXAMETHASONE: IT IS A CORTICOSTEROID WHICH FAVOURS DECREASED PRODUCTION OF INFLAMMATORY MEDIATORS, INHIBITION OF PHOSPHOLIPASE A2 AND CHANGES IN CELL FUNCTION INDUCED BY GLUCOCORTICOID
Sponsors
DIVYA SINGH
Eligibility
Inclusion criteria
Inclusion criteria: PATIENTS POSTED FOR HEAD, NECK AND FACE SURGERIES UNDER GENERAL ANESTHESIA WITH ENDOTRACHEAL INTUBATION. PATIENTS WHO ARE CLASSIFIED WITH ASA GRADE I OR II. PATINETS WHO ARE CLASSIFIED WITH MALLAMPATI SCORE 1 OR 2.
Exclusion criteria
Exclusion criteria: PATIENTS WITH HISTORY OF RECENT AND/OR ACTIVE UPPER RESPIRATORY TRACT ILLNESS. PATIENTS WHO ARE CHRONIC SMOKERS. PATIENTS WITH ANTICIPATED DIFFICULT AIRWAY. PATIENTS WITH HISTORY OF PREOPERATIVE SORE THROAT. PATIENTS WITH KNOWN ALLERGY TO STUDY DRUG. PREOPERATIVE USE OF ANALGESIC DRUGS, LIKE NSAIDS OR OPIOIDS OR STEROIDS.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| INCIDENCE AND/OR SEVERITY OF POSTOPERATIVE SORE THROAT AMONG THREE DRUGS GROUPS NAMELY KETAMINE, DEXMEDETOMIDINE AND DEXAMETHESONE SOAKED PHARYNGEAL PACKS.Timepoint: BASELINE, AFTER INDUCTION, JUST BEFORE INTUBATION, AFTER PHARYNGEAL PACKING, POST EXTUBATION IMMEDIATELY, 2 HOURS, 4 HOURS, 8 HOURS, 12 HOURS, 24 HOURS. | — |
Secondary
| Measure | Time frame |
|---|---|
| ASSESSING THE PATIENTS FOR INTENSITY OF SORE THROAT, HEMODYNAMIC CHANGES (FOR EXAMPLE: HEART RATE, BLOOD PRESSURE)Timepoint: BASELINE, AFTER INDUCTION, JUST BEFORE INTUBATION, AFTER PHARYNGEAL PACKING, POST EXTUBATION IMMEDIATELY, 2 HOURS, 4 HOURS, 8 HOURS, 12 HOURS, 24 HOURS. | — |
Countries
India
Contacts
Public ContactDR SUKRITI ATRAM
GRANT GOVERNMENT MEDICAL COLLEGE AND SIR JJ HOSPITAL
Outcome results
None listed