None listed
Conditions
Interventions
Intervention1: 25 Percent Dextrose: Prolotherapy with 1 mL of 25 percent dextrose solution injected into the retrodiscal tissue and inferior joint space of the temporomandibular joint (TMJ).
Control I
Sponsors
Dr Jyothsna M
Eligibility
Inclusion criteria
Inclusion criteria: 1. Patients aged between 18 to 50 years diagnosed with TMD. 2. Patients ready to give informed consent and willingness to comply with follow-up visits. 3. Presence of persistent TMJ pain for more than 3 months. 4. Limited jaw mobility or joint noises (clicking, crepitations) associated with TMD. 5. Has not undergone any prior treatment for TMD.
Exclusion criteria
Exclusion criteria: 1. History of TMJ surgery or severe TMJ degenerative disease. 2. Presence of systemic inflammatory conditions (e.g., rheumatoid arthritis, lupus) or blood dyscrasias are excluded from the study. 3. Recent use of corticosteroid injections. 4. Pregnancy or lactation. 5. Active infection or tumor in the injection site. 6. Severe psychiatric disorders that may affect pain perception and compliance.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Efficacy of 12.5 percent versus 25 percent dextrose prolotherapy on temperomandibular joint dysfunction on pain using VAS scale, maximum mouth opening using interincisal distance, TMJ tenderness checked by palpation, presence or absence of TM joint sounds(clicking/crepitations) checked by palpation.Timepoint: Post operative 2 weeks, 4 weeks, 1 month and 3 months | — |
Secondary
| Measure | Time frame |
|---|---|
| 1. Presence or absence of deviation during mouth opening. Timepoint: Baseline, 2 weeks, 4 weeks, 1 month, 3 months.;2. Any adverse events related to injection (swelling, prolonged pain)Timepoint: Within 48 hours and at each follow up | — |
Countries
India
Contacts
Public ContactDr Prasanna Kumar D
KVG Dental College and Hospital
Outcome results
None listed