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A clinical study to explore additional effects of Ayurvedic Fennel Eye Drops with Timolol eye drops in Glaucoma patients

Randomized controlled clinical study to assess the add-on effect of Mishreya (Foeniculum vulgare) Ark ashchyotan with Timolol eye drops in primary open angle glaucoma (POAG) with special reference to Kaphaja Adhimantha. - MARK eye drops

Status
Active, not recruiting
Phases
Phase 2Phase 3
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2026/02/103348
Enrollment
114
Registered
2026-02-09
Start date
Unknown
Completion date
Unknown
Last updated
2026-03-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: H401- Open-angle glaucoma

Interventions

None listed

Sponsors

Ayurved Vidya Prasarak Mandals Ayurved Mahavidyalay, Sion
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 40 -70 years old patient of POAG, with IOP less than 30 mm of Hg, CDR less than 0.7, visual acuity more than 6/60

Exclusion criteria

Exclusion criteria: 1. Patients with all types of PCAG, cataract, secondary and developmental glaucoma including exfoliative glaucoma, pigmentary glaucoma, trauma induced inflammatory glaucoma, advanced glaucomatous optic neuropathy or optic atrophy. 2. Visual acuity less than 6/60 3. known cases of bronchial asthma, cardiac diseas or patient on steroid treatment

Design outcomes

Primary

MeasureTime frame
1. To assess the changes in subjective symptoms of POAG (Kaphaj Adhimantha) in group A and group B. 2. To assess the pre and post study changes in BCVA, IOP, MD in Perimetry, NPA in RAF rule in group A and group B. 3. To study the efficacy of Mishreya Ark Ashchyotan and Timolol eye drops in POAG. Timepoint: at baseline, 10th day, 20th day, 30th day, 60th day

Secondary

MeasureTime frame
3. To study Mishreya ark in detail 4. To study Ashchyotan in deatil and prepare its SOP. 3. To study probable mode of action of Mishreya Ark Ashchyotan.Timepoint: at baseline, 10th day, 20th day, 30th day, 60th day

Countries

India

Contacts

Public ContactDr Ravidas Wamanrao More

Ayurved Vidya Prasarak Mandals Ayurved Mahavidyalay Sion

ravimore67@gmail.com9967483930

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Mar 14, 2026