Health Condition 1: H441- Other endophthalmitis
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: Patients aged 18 years and above Patients admitted to HDU and ICU for greater than or equal to 48 hours Patients with clinical or laboratory evidence of systemic infection sepsis or risk factors associated with hematogenous spread such as central line indwelling catheter immunosuppression Patients who develop ocular symptoms such as eye pain redness vision changes or those who are identified through routine ophthalmologic screening
Exclusion criteria
Exclusion criteria: Patients with pre existing ocular infection or active endophthalmitis prior to ICU and HDU admission Patients with exogenous endophthalmitis following ocular trauma or surgery Patients with ocular malignancy or metastatic ocular lesions that mimic endophthalmitis
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| prevalence and incidence rate of EE in ICU and HDU settings Risk Factor Identification Microbiological and Clinical Profile Characterization Diagnostic and Therapeutic Timeline Assessment Visual and Anatomical Outcomes Measurement Evidence for Clinical Guidelines to provide real world data Public Health Relevance to contribute to regional and national databases Timepoint: Assessed at baseline after recruitment and 1 week or at the time of discharge whichever earlier | — |
Secondary
| Measure | Time frame |
|---|---|
| Evidence for Clinical Guidelines Provide real world data to advocate for routine ophthalmic screening in ICU & HDU patients with systemic infections or sepsis Lay the foundation for future prospective interventional trials or screening protocols in critical care settings Public Health Relevance Contribute to regional & national databases on hospital acquired ocular infections Influence infection control & antimicrobial stewardship policies involving ocular manifestations in ICU protocol Timepoint: Assessed at baseline after recruitment & 1 week or at the time of discharge whichever earlier | — |
Countries
India
Contacts
All India Institute of Medical Sciences Guwahati