Health Condition 1: O- Medical and Surgical
Conditions
Interventions
Intervention1: Evaluate analgesic efficacy of epidural morphine when added to 0.2 % ropivaciane for management of pain following total knee arthroplasty.: Group A 3mg morphine added to 0.2% ropivac
Sponsors
Dayanand Medical college and Hospital
Eligibility
Inclusion criteria
Inclusion criteria: ASA grade I to grade III
Exclusion criteria
Exclusion criteria: 1. Any contraindication to neuraxial blockade 2. Allergy or hypersensitivity to morphine or local anesthetics 3. History of chronic opioid use or substance abuse 4. Significant respiratory disease (e.g. severe chronic obstructive pulmonary disease or sleep apnea) 5. Renal insufficiency requiring dialysis 6. Severe hepatic impairment 7. Inability to use the numeric pain rating scale e.g. cognitive impairment or language barrier 8. Patients with high body mass index 9. ASA grade IV and higher
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Total rescue analgesia consumption in 24 hoursTimepoint: Patient will be observed at the time of administration of the study drug , then every hourly till 4 hours and then every hourly till 24 hours | — |
Secondary
| Measure | Time frame |
|---|---|
| Post operative pain scores as assessed by NRSTimepoint: Patient will be observed at the time of administration of the study drug , then every hourly till 4 hours and then every hourly till 24 hours | — |
Countries
India
Contacts
Public ContactDr Amisha Gupta
Dayanand Medical College and Hospital
Outcome results
None listed