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Comparison of how dexmedetomidine and ketamine affect pain relief after lower limb fracture surgeries done under a spinal block

Comparison of the effect of intravenous dexmedetomidine and ketamine on postoperative analgesia in lower limb fracture surgeries under subarachnoid block - nil

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
CTRI
Registry ID
CTRI/2026/02/103309
Enrollment
50
Registered
2026-02-09
Start date
Unknown
Completion date
Unknown
Last updated
2026-03-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: T07- Unspecified multiple injuries

Interventions

Intervention1: Nil: Nil Intervention2: Nil: Nil Intervention3: Nil: Nil

Sponsors

Government medical college Kozhikode
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1.Patients posted for lower limb fracture surgeries 2.ASA PS I and II

Exclusion criteria

Exclusion criteria: 1.Patients allergic to dexmedetomidine or ketamine 2.Patients with ischemic heart disease, severe renal and liver impairment 3.Patients on beta blockers 4.Duration of surgery more than 120 minutes

Design outcomes

Primary

MeasureTime frame
To compare postoperative analgesia in terms of duration of analgesia, total rescue analgesia and NRS pain scoresTimepoint: Postoperative analgesia will be evaluated by Numerical rating scale at 0,1,2,4,6,12 & 24 hours from stopping infusion of study drug.—

Secondary

MeasureTime frame
To compare intraoperative & postoperative sedation scores Timepoint: Intraoperatively every 30 minutes from administration of bolus dose of study drug. postoperatively at 0,1,2,4,6,12 & 24 hours from stopping infusion of study drug.;To assess side effects like hemodynamic instabilityTimepoint: Hemodynamics will be monitored every 5 minutes intraoperatively.—

Countries

India

Contacts

Public ContactDr Shafna K T

Government medical college, Kozhikode

shafnakt87@gmail.com8506911421

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Mar 14, 2026