A Study Comparing Two Materials to Improve Healing of Gum Bone Defects After Gum Surgery

Comparative Evaluation of Healing in Periodontal Suprabony Defects Following open flap debridement with enamel matrix derivative vs Hyaluronic Acid application- A Randomized Controlled Trial - NIL

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2026/02/103306

Enrollment

Registered

2026-02-09

Start date

Unknown

Completion date

Unknown

Last updated

2026-03-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K053- Chronic periodontitis

Interventions

Intervention1: Hyaluronic Acid gel: After opening flap in suprabony defect hyaluronic acid will be applied at root surface of tooth and then sutures will be taken Control Intervention1: Enamel Matrix

Eligibility

Inclusion criteria

Inclusion criteria: Stage III periodontitis Grade A/ B

Exclusion criteria

Exclusion criteria: Systemic Disease Prolonged antibiotic usage Prolonged Anti inflammatory drugs Pregnant/ Lactating Females Increased Tooth Mobility Multirooted teeth with furcation involvement

Design outcomes

Primary

Measure	Time frame
Probing pocket depth Gingival Recession Clinical attachment levelTimepoint: At baseline,3 months, 6 months	—

Secondary

Measure	Time frame
Full mouth plaque score Full mouth bleeding scoreTimepoint: At baseline,3 months, 6 months	—

Countries

India

Contacts

Public ContactDr Nayana Patel

Government dental college and hospital , Jamnagar

drnayanagpatel@gmail.com9825191911

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Mar 14, 2026