Assessment of bone activity around dental implants placed in type 2 Diabetes Mellitus patients after giving them ultrasound(LIPUS) therapy

Assessment of osteoblastic activity around dental implants following Low-Intensity Pulsed Ultrasound (LIPUS) therapy in patients with type 2 Diabetes Mellitus: A split-mouth randomised controlled trial - NIL

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2026/02/103272

Enrollment

Registered

2026-02-09

Start date

Unknown

Completion date

Unknown

Last updated

2026-03-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K068- Other specified disorders of gingiva and edentulous alveolar ridge

Interventions

Intervention1: Low Intensity Pulsed Ultrasound(LIPUS) therapy: Low-Intensity Pulsed Ultrasound (LIPUS) therapy will be applied to the experimental implant site following implant placement. LIPUS will

Eligibility

Inclusion criteria

Inclusion criteria: 1. Partially edentulous participants with bilaterally missing mandibular posterior teeth willing for implant-supported prosthesis. 2. Patients aged between 21 to 60 years. 3. Patients with Controlled Type 2 Diabetes Mellitus (HbA1c level 5.7 to 8%).

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

Measure	Time frame
To asses the osteoblastic activity around dental implants in patients with Type 2 Diabetes Mellitus using bone scintigraphy Timepoint: 30 days, 60 days, 90 days	—

Secondary

Measure	Time frame
To asses the osteoblastic activity around dental implants in patients with Type 2 Diabetes Mellitus using Alkaline phosphatase (ALP) assay.Timepoint: 30 days, 90 days;To asses the Patient Related Outcome Measures (PROMs) regarding the LIPUS therapy using Visual Analog Scale (VAS).Timepoint:	—

Countries

India

Contacts

Public ContactSarvesh Kulkarni

Sri Ramachandra Dental College and Hospital

shanmuganathan.n@sriramachandra.edu.in9840231829

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Mar 14, 2026