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A study to see whether adding a steroid medicine improves pain relief from a nasal nerve block in patients with facial nerve pain

A comparative study of dexamethasone combined with lignocaine and lignocaine alone in sphenopalatine ganglion block in patients with trigeminal neuralgia affecting the maxillary (V2) distribution: A randomised controlled trial - nil

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2026/02/103205
Enrollment
36
Registered
2026-02-06
Start date
Unknown
Completion date
Unknown
Last updated
2026-03-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: G500- Trigeminal neuralgia

Interventions

Intervention1: dexamethasone combined with lignocaine in SPG block in patients with TGN of v2 distribution: Lignocaine plus dexamethasone SPG block dexamethasone 8mg dipped in cotton tipped applicator

Sponsors

AIIMS New Delhi
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Age 18 80 years. Predominant unilateral pain in maxillary V2 distribution Diagnosis of idiopathic TN Inadequate relief or intolerance to standard medical therapy.

Exclusion criteria

Exclusion criteria: Allergy to lignocaine, steroids, or local contraindications. Pain of mixed origin Coagulopathy or on anticoagulants Local infection at injection site. Prior SPG block or PRF within 4 weeks Pregnancy. Patient refusal

Design outcomes

Primary

MeasureTime frame
Change in Numerical Rating Scale NRS 0 to 10 from baseline to 1 week post block. Timepoint: Change in Numerical Rating Scale NRS 0 to 10 from baseline to 1 week post block.

Secondary

MeasureTime frame
NRS at 30 minutes, 1 hour and at 1 week after the block. Number of rescue doses of 10 percent lignocaine spray and oral rescue medicine used over the week. Adverse events like nasal irritation, epistaxis, throat discomfort, dizziness, or systemic effects. Duration of pain reliefTimepoint: 30 minutes, 1 hour and 1 week

Countries

India

Contacts

Public ContactDr Heena Garg

Department of Anaesthesiology, Pain medicine and Critical Care, AIIMS

gargheena11@gmail.com9464533877

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Mar 14, 2026