A Clinical Study to Evaluate Gum Health Around Dental Implants After Fixing the Crown.

EFFECT OF INDOCYANINE GREEN MEDIATED PHOTODYNAMIC THERAPY ON PERIODONTAL INFLAMMATORY MARKERS TUMOR NECROSIS FACTOR- ALPHA AND MATRIX METALLOPROTEINASE 8 AROUND PERI-IMPLANT SULCUS AFTER PLACEMENT OF CROWN- A RANDOMIZED CLINICAL TRIAL - NIL

Status

Active, not recruiting

Phases

Phase 2

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2026/02/103196

Enrollment

Registered

2026-02-06

Start date

Unknown

Completion date

Unknown

Last updated

2026-03-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K036- Deposits [accretions] on teeth

Interventions

Intervention1: Indocyanine green mediated photodynamic therapy on periodontal inflammatory marker MMP-8: Scaling and root planing will be done using hand and ultrasonic instrumentation with Implacare

Eligibility

Inclusion criteria

Inclusion criteria: Systematically healthy individuals, Presence of at least one screw type titanium endosseous dental implants at different sites, No implant mobility, No evidence of occlusal overload, Dental implant which has not elicited signs and symptoms of peri-implant mucositis or peri-implantitis

Exclusion criteria

Exclusion criteria: Individuals who have history is antimicrobial and anti-inflammatory therapy in last 3 months, Subjects with diabetes mellitus, hypertension,heart disease,rheumatoid arthritis,tumors, Pregnant/lactating women, Smokers

Design outcomes

Primary

Measure	Time frame
Gingival index, Bleeding and probing, Probing pocket depth, Mucosal recession,Clinical attachment loss, MMP-8 and TNF-alpha biomarkers in the peri-implant sulcular fluid at baseline and 4 monthsTimepoint: At baseline and 4 months	—

Secondary

Measure	Time frame
NilTimepoint: Nil	—

Countries

India

Contacts

Public ContactPriyanka Gupta

The Oxford dental college

amitacou@yahoo.co.in09886789080

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Mar 14, 2026