To compare the effects of transversus thoracis block versus intercostal block for pain relief after open heart surgeries.

A randomized comparative study for the efficacy of bilateral transversus thoracis muscle plane block versus parasternal intercostal block for perioperative opioid consumption in patients undergoing cardiac surgeries. - NIL

Status

Active, not recruiting

Phases

Phase 2

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2026/02/103173

Enrollment

Registered

2026-02-06

Start date

Unknown

Completion date

Unknown

Last updated

2026-03-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical

Interventions

Intervention1: Group A= Bilateral transversus thoracis muscle plane block: Patients undergoing valvular cardiac surgery under GA and receiving bilateral USG guided transversus thoracis muscle plane bl

Eligibility

Inclusion criteria

Inclusion criteria: 1. Patients giving informed written consent. 2. Patients of age 18 years to 70 years scheduled for elective open heart valvular surgery via median sternotomy. 3. Subjects with ASA grade 2 to 3.

Exclusion criteria

Exclusion criteria: 1. Patients taking part in any other study. 2. Patients with history of opioid abuse. 3. Allergic to local anesthetics. 4. Impaired cerebral functions. 5. Inability to understand or operate the PCA pump. 6. Patients with Body Mass Index more than 30 kg per m2. 7. Patients with local site infections or burns.

Design outcomes

Primary

Measure	Time frame
To assess the difference in perioperative opioid requirement between the two groups.Timepoint: Assessed immediately, 2,4,6,12,18,24,30,36,42 and 48 hours post extubation.	—

Secondary

Measure	Time frame
1. To assess and compare the time for need of first dose of rescue analgesia (Injection Fentanyl intravenously in both groups). 2. To assess the difference in postoperative Visual Analogue Scale between the two groups. 3. To assess and compare hemodynamic response between the study groups. 4. To assess and compare postoperative PEFR after extubation in both the study groups. 5. Side effects and complications if any in both groups.Timepoint: Assessed immediately, 2,4,6,12,18,24,30,36,42 and 48 hours post extubation.	—

Measure

Time frame

1. To assess and compare the time for need of first dose of rescue analgesia (Injection Fentanyl intravenously in both groups). 2. To assess the difference in postoperative Visual Analogue Scale between the two groups. 3. To assess and compare hemodynamic response between the study groups. 4. To assess and compare postoperative PEFR after extubation in both the study groups. 5. Side effects and complications if any in both groups.Timepoint: Assessed immediately, 2,4,6,12,18,24,30,36,42 and 48 hours post extubation.

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Countries

India

Contacts

Public ContactDr Swati Singh

Sawai Mansingh Medical College, Jaipur

reemadr.rn@gmail.com9413237117

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Mar 14, 2026