Comparison of herbal and chemical mouthwash in patients with gum disease

Comparative evaluation of the efficacy of Moringa oleifera mouthwash versus 0.2% Chlorhexidine gluconate mouthwash as an adjunct to scaling and root planing in the treatment of patients with chronic generalized gingivitis-A clinical study - Not

Status

Active, not recruiting

Phases

Phase 1Phase 2

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2026/02/103165

Enrollment

Registered

2026-02-06

Start date

Unknown

Completion date

Unknown

Last updated

2026-03-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

Intervention1: Subjects will be asked to rinse their mouth with Moringa oleifera mouthwash twice a day for 20 days.: All the subjects will undergo an oral examination on day 1 (baseline) of the study.

Eligibility

Inclusion criteria

Inclusion criteria: Both genders with age 25 to 55 years, Systemically healthy subjects, Subjects who have been diagnosed by a periodontist with moderate to severe chronic generalized gingivitis definition will be based on classification of periodontitis as proposed in 2017 World Workshop, Healthy subjects with no history of allergy to any ingredient in mouthwash, Subjects having moderate-to-severe gingivitis, with plaque index (PI) score less than ,gingival index (GI) less than 1, and papillary bleeding index (PBI) less than 1

Exclusion criteria

Exclusion criteria: Subjects with history of systemic disease including diabetes mellitus,cardiovascular, cancer, significant hepatic and renal impairment, neurologic and psychiatric disorder, and immunodeficiency, Subjects who had received periodontal treatment during the 6 months before the study, Pregnant or lactating women, Subjects who had taken antibiotics or anti-inflammatory drugs within the last three months, Subjects who have habits of smoking or drinking alcohol, Subjects with periodontitis stage III and stage IV.

Design outcomes

Primary

Measure	Time frame
The Following clinical parameters will be recorded Gingival index (GI), Plaque Index (PI), Bleeding and probing, Probing pocket depths (PPD)at baseline and after 20 days at baseline( day 1) and after 20 day.Timepoint: The Following clinical parameters will be recorded Gingival index (GI), Plaque Index (PI), Bleeding and probing, Probing pocket depths (PPD)at baseline and after 20 days at baseline( day 1) and after 20 day.	—

Measure

Time frame

The Following clinical parameters will be recorded Gingival index (GI), Plaque Index (PI), Bleeding and probing, Probing pocket depths (PPD)at baseline and after 20 days at baseline( day 1) and after 20 day.Timepoint: The Following clinical parameters will be recorded Gingival index (GI), Plaque Index (PI), Bleeding and probing, Probing pocket depths (PPD)at baseline and after 20 days at baseline( day 1) and after 20 day.

—

Secondary

Measure	Time frame
nilTimepoint: nil	—

Countries

India

Contacts

Public ContactPriyanka Gupta

The Oxford Dental College

guptadrpriyanka22@gmail.com9279068445

Outcome results