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Assessment of benefits of Two Desensitizing Toothpastes (Toothmin and Perfora) for Tooth Sensitivity and evaluation of its effect in Saliva composition

The Effect of commercially Available Toothpast (Toothmin & Perfora) on Salivary Biomarkers and Clinical Parameters in Patients with Dentinal Hypersensitivity: A Randomized Controlled Trial - NIL

Status
Active, not recruiting
Phases
Phase 2Phase 3
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2026/02/103126
Enrollment
21
Registered
2026-02-05
Start date
Unknown
Completion date
Unknown
Last updated
2026-03-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

Intervention1: performa &Toothmin toothpaste: the study participants will be asked to use this toothpaste twice daily using provided tooth brush. They will be asked to use for 6 weeks Control Interven

Sponsors

Nisha Nayak
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: systemically helathy male and female pt woth age range of 25-65yrs willing to participate in the study patients having positive response for at least two teeth on clinical examination for dentinal hypersensitivity

Exclusion criteria

Exclusion criteria: pregnant and lactating woman patient who is already on treatment for dentinal hypersensitivity pateint with allergy patent who are receiving treatment for GERD patients with systemic illness or any other oral pathology

Design outcomes

Primary

MeasureTime frame
reduction in dentinal hypersensitivity by VAS and air blast test at baseline, end of 2 weeks and six weeks salivary calcium and phosphate levels at baseline, 2 weeks and end of 6 weeksTimepoint: Baseline, 2 weeks 6 weeks

Secondary

MeasureTime frame
nilTimepoint: nil

Countries

India

Contacts

Public ContactSangeeta Umesh nayak

Manipal College of Dental Sciences Mangalore

sangeeta.nayak@manipal.edu9880718372

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Mar 14, 2026