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comparision of two neuromuscular blocking agents

Comparison of effectiveness of Inj. Vecuronium bromide with Inj. Rocuronium bromide for tracheal intubation in elective surgery under general Anaesthesia : Prospective randomized double blinded control study. - NIL

Status
Active, not recruiting
Phases
Phase 2
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2026/02/103111
Enrollment
70
Registered
2026-02-05
Start date
Unknown
Completion date
Unknown
Last updated
2026-03-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K929- Disease of digestive system, unspecified Health Condition 2: K319- Disease of stomach and duodenum, unspecified Health Condition 3: N289- Disorder of kidney and ureter, unspecified Health Condition 4: K87- Disorders of gallbladder, biliarytract and pancreas in diseases classified elsewhere Health Condition 5: C509- Malignant neoplasm of breast of unspecified site Health Condition 6: C73- Malignant neoplasm of thyroid gland Health Condition 7: C029- Malignant neoplasm of

Interventions

Intervention1: inj rocuronium: inj rocuronium given intravenous in the dose og 0.6mg per kg at the time of intubation Control Intervention1: Inj. Vecuronium: inj vecuronium given intravenous in the do

Sponsors

Sir T Hospital
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Patients who are willing to give consent to participate in the study. Patients scheduled for elective surgery under general anaesthesia Patients of age between 20 to 60 years of either gender Patients with ASA grade I and II. Patients with BMI of 18 to 25 .

Exclusion criteria

Exclusion criteria: Patient having history of drug allergy to study drug. Patient with renal and hepatic dysfunction. Patient with neuromuscular disorder or medication known to influence neuromuscular functions. Patients with anticipated difficult intubation.

Design outcomes

Primary

MeasureTime frame
Assessed using stsndardized intubation scoring system based on jaw relaxation, vocal cord posotion and patient response (excellent/good/poor) Timepoint: 60 sec after administration of study drug

Secondary

MeasureTime frame
To compare hemodynamic parameters (MAP , Heart rate and Oxygen saturation )in both groups. To compare side effects and complications if any in both the groupsTimepoint: Before intubation, after intubation 5, 15, 30, 45, 60, 75 and 90min

Countries

India

Contacts

Public ContactDr Poonam verma

GMC Bhavnagar

dr.chandrika62@gmail.com9998994194

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Mar 14, 2026