Health Condition 1: F321- Major depressive disorder, singleepisode, moderate
Conditions
Interventions
Intervention1: high definition transcranial direct current stimulation with intermittent theta burst stimulation in active patients: Patient will be given HDtDCS by placing anode at the left dorsolate
Sponsors
Sri Guru Ram Rai Institute of medical and health sciences
Eligibility
Inclusion criteria
Inclusion criteria: 1.Patient with a diagnosis of Major Depressive Disorder based on diagnostic criteria of the Diagnostic and Statistical Manual of Mental Disorders Fifth Edition 2.Patients aged between 18 to 59 years 3.Right handed patients 4.Illness severity with HAM D score more than 20
Exclusion criteria
Exclusion criteria: 1.Any other major mental disorders. 2.Any other Substane use disorder except nicotine and caffeine. 3.Patient is uncooperative for the procedure. 4.Patients with neurological disorders with history of epilepsy, organic brain damage or any neurological procedures 5.Patients with implanted metallic devices 6.Patients receiving ECT in past 6 months. 7.Patients with significant unstable medical conditions like uncontrolled hypertension, complicated diabetes mellitus, organic failures, etc.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| To compare the quantitative change in depressive symptoms in patients suffering from Major Depressive disorder following high definition transcranial direct current stimulation with intermittent theta burst stimulation, compared to combined sham stimulation.Timepoint: day 0, day 15, day 30 | — |
Secondary
| Measure | Time frame |
|---|---|
| To compare the change of quality of life following high definition transcranial direct current stimulation with intermittent theta burst stimulation, compared to combined sham stimulation in patients suffering from Major Depressive disorder.Timepoint: day 0, day 15, day 30 | — |
Countries
India
Contacts
Public ContactDr Kirat Kaur
Sri Guru Ram Rai Institute of medical and health sciences
Outcome results
None listed