Health Condition 1: K121- Other forms of stomatitis
Conditions
Interventions
Intervention1: Chlorhexidine mouth wash: Dose: 15ml, 0.12% chlorhexidine gluconate mouthwash (Peridex)
Frequency: twice daily
Route: Topical Transmucosal
Duration: Phase I (4 weeks), Phase II (4 week
Sponsors
Alok Dubey
Eligibility
Inclusion criteria
Inclusion criteria: Adolescents planned for fixed orthodontic treatment with an expected more than 12 months duration. Healthy individuals free from systemic diseases. Non-smokers. No history of hypertension or cardiovascular disorders. Willingness to participate in the study and comply with the protocol.
Exclusion criteria
Exclusion criteria: Presence of systemic illness or cardiovascular disorders. Psychological or physical disabilities interfering with participation. Obese children. (Sex specific BMI range is 95th percentile or greater) Plans to relocate within 12-14 months, leading to potential loss of follow-up. Known allergies or adverse reactions to chlorhexidine mouthwash.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| This study aims to provide clinically significant data regarding the systemic impact of long-term chlorhexidine mouthwash use on nitric oxide bioavailability and blood pressure in adolescents.Timepoint: Phase I: Baseline reading, Record clinical readings at weekly intervals over 4 weeks. Phase II: After a 3-month washout period, resume CHX use and again record weekly readings for another 4 weeks at weekly intervals. | — |
Secondary
| Measure | Time frame |
|---|---|
| NILTimepoint: NIL | — |
Countries
India
Contacts
Public ContactAlok Dubey
Narsinhbhai Patel Dental College And Hospital
Outcome results
None listed