Health Condition 1: C539- Malignant neoplasm of cervix uteri, unspecified
Conditions
Interventions
Intervention1: KD
KR: in KD group ketamine is used along with dexmedetomidine and in KR group ketamine is used with remifentanil and MRSS (0-6) will be recorded immediately after induction, every 5 mi
Sponsors
vivek vishal
Eligibility
Inclusion criteria
Inclusion criteria: - Patient is willing to participate - BMI between 20 and 30 kg/m 2 - ASA GRADE - I, II, III - MPG class 1 to 2
Exclusion criteria
Exclusion criteria: - Allergy to the drugs being used in the study - Acute or chronic hepatic disease, renal disease, cardiovascular disease, central nervous system disease, psychiatric illness, alcohol or substance addiction, endocrine disorder.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| To compare the sedation efficacy of ketamine with dexmedetomidine versus ketamine with remifentanil using the Modified Ramsay sedation score. and the use of rescue doses of ketamine. Timepoint: after premedication (before induction), just after induction, at 3min, 5min and thereafter every 5 min intra-operatively, at the end of procedure, postoperatively every 5 min, till Aldrete score 10 | — |
Secondary
| Measure | Time frame |
|---|---|
| 1. To determine in which of the two groups received a rescue dose of ketamine. 2. To compare the sedation time, procedure time, awakening time, recovery time, and surgeon satisfaction. 3. To compare the hemodynamic changes, such as heart rate, blood pressure 4. To compare any side effects during the procedure, like hypotension, bradycardia, or any other. Timepoint: after premedication (before induction), just after induction, at 3min, 5min and thereafter every 5 min intra-operatively, at the end of procedure, postoperatively every 5 min, till Aldrete score 10 | — |
Countries
India
Contacts
Public ContactVIVEK VISHAL
INDIRA GANDHI INSTITUTE OF MEDICAL SCIENCES PATNA
Outcome results
None listed