Comparing Laser Therapy and MMP-9 Levels in Healing After Gum Surgery in Patients with Long-Term Gum Disease: A Study Using Two Sides of the Mouth

COMPARISON OF LOW-LEVEL LASER THERAPY AND MMP-9 LEVELS ON WOUND HEALING FOLLOWING OPEN FLAP DEBRIDEMENT IN CHRONIC PERIODONTITIS PATIENTS: A SPLIT-MOUTH RANDOMIZED CONTROL TRIAL - NIL

Status

Active, not recruiting

Phases

Phase 3Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2026/02/103082

Enrollment

Registered

2026-02-05

Start date

Unknown

Completion date

Unknown

Last updated

2026-03-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K053- Chronic periodontitis

Interventions

Intervention1: Open flap debridement: The surgical area is likely to be anesthetized using local anaesthetic (2% lignocaine with adrenaline 1:80,000).To reflect a full-thickness mucoperiosteal flap, i

Eligibility

Inclusion criteria

Inclusion criteria: Patients in the age group of 25 to 60 years Patients should be systematically healthy Chronic Periodontitis patients, probing depth greater than or equal to 5mm Patients who have not undergone periodontal therapy in the past 6 months

Exclusion criteria

Exclusion criteria: Patients who are smokers, alcoholics or tobacco chewers. Patients not willing to participate in the study or not available for follow up. Pregnant and lactating women Intake of drugs that affect on periodontal disease clinical symptoms (eg, long-term steroid use or calcium channel blocker)

Design outcomes

Primary

Measure	Time frame
Wound Healing and MMP 9 levelsTimepoint: Baseline and 3 months	—

Secondary

Measure	Time frame
Clinical IndicesTimepoint: Baseline and 3 months	—

Countries

India

Contacts

Public ContactDr Daya S

Bapiji Dental College and Hospital

dayas55@gmail.com8746818249

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Mar 14, 2026