This study compares sodium dichloroisocyanurate and calcium hydroxide in killing bacteria during root canal treatment. The medicines are placed inside the tooth between sessions, and bacteria counts are checked before and after. Goal is to see which medicine works better

Comparative evaluation of antimicrobial efficacy of Sodium Dichloroisocyanurate and Calcium Hydroxide as a root canal medicament in non- vital teeth: A Randomized Double Blinded Clinical Study - NIL

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2026/02/103075

Enrollment

Registered

2026-02-05

Start date

Unknown

Completion date

Unknown

Last updated

2026-03-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: 8- Other Procedures

Interventions

Intervention1: Sodium Dichloroisocyanurate: To evaluate and compare antimicrobial efficacy of Sodium Dichloroisocyanurate and Calcium Hydroxide as a root canal medicament in non- vital teeth (in terms

Eligibility

Inclusion criteria

Inclusion criteria: 1. Systemically Healthy patient who will give informed consent will be included. 2. Completely matured multi-rooted tooth, diagnosed with pulp necrosis will be included.

Exclusion criteria

Exclusion criteria: 1. Teeth with immature roots, symptomatic irreversible pulpitis, symptomatic reversible pulpitis, those diagnosed with, cracks, internal/external root resorption or pulp canal obliteration and exhibiting clinical and/or radiographic signs of chronic/severe periodontitis or periapical abscess will be excluded. 2. Teeth with previously endodontic treatment will be excluded. 3. Patients with severe periodontitis and poor oral hygiene will be excluded from the study. 4. Pregnant or lactating women will be excluded

Design outcomes

Primary

Measure	Time frame
3.To compare antimicrobial efficacy of Sodium Dichloroisocyanurate and Calcium Hydroxide as a root canal medicament in non- vital teeth.Timepoint: baseline and 7 days	—

Secondary

Measure	Time frame
NILTimepoint: NIL	—

Countries

India

Contacts

Public ContactDr Nimisha Shah

K.M. Shah Dental College and Hospital Gujarat

nshah7873@gmail.com9998994299

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Mar 14, 2026