A Study Comparing Recovery After Laparoscopic Surgery Using TWO Anesthesia Gases : Desflurane and Sevoflurane

Comparison of the recovery profiles of desflurane with sevoflurane in patients undergoing laparoscopic surgery : A prospective randomized double blind clinical study - Nil

Status

Active, not recruiting

Phases

Phase 2

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2026/02/103058

Enrollment

Registered

2026-02-05

Start date

Unknown

Completion date

Unknown

Last updated

2026-03-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K808- Other cholelithiasis Health Condition 2: K469- Unspecified abdominal hernia without obstruction or gangrene Health Condition 3: K37- Unspecified appendicitis

Interventions

Intervention1: Desflurane : Inhalant agent during surgery Route-Inhalational dose concentration-3-6% Time -Start inhalational agent from induction of OT upto skin closure Control Intervention1: Sevofl

Eligibility

Inclusion criteria

Inclusion criteria: 1) Patient willing to give consent to participate in the study group 2) ASA grade 1 and 2 3) BMI 18 to 25

Exclusion criteria

Exclusion criteria: 1) Patient with history of drug allergy to study drug 2) Patient with moderate to sever cardiopulmonary, hepatic renal dysfunction 3) Patient with difficult airway

Design outcomes

Primary

Measure	Time frame
Time for eye opening from discontinuation anesthetic agent Time for Verbal response from discontinuation anesthetic agent Time From Skin Closure to extubation from discontinuation anesthetic agent Time for achieving modified aldrete score = 9Timepoint: Time from discontinuation of anesthetic agent comparison of changes in hemodynamic parameters in between two groups at baseline ,aftr 5 min,after 10 min, after 15 min, after 30 min,after60 min,after 90 min,after 120 min	—

Measure

Time frame

Time for eye opening from discontinuation anesthetic agent Time for Verbal response from discontinuation anesthetic agent Time From Skin Closure to extubation from discontinuation anesthetic agent Time for achieving modified aldrete score = 9Timepoint: Time from discontinuation of anesthetic agent comparison of changes in hemodynamic parameters in between two groups at baseline ,aftr 5 min,after 10 min, after 15 min, after 30 min,after60 min,after 90 min,after 120 min

—

Secondary

Measure	Time frame
Time to extubation and orientation Hemodynamic parameter Modified aldrete score and time to PACU discharge Incidence of postoperative nausea, vomiting and airway eventsTimepoint: Baseline, after extubation 5min, 10min, 15min, 30min, 60min, 90 min, 120min	—

Countries

India

Contacts

Public ContactDr Hemant Madhukar Rautmale

GMC Bhavnagar

drshilpadoshi@yahoo.in9428810763

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Mar 14, 2026