For large renal stones, surgery of choice is key hole procedure called PCNL. This trial compares 2 different techniques of PCNL in patients who have large renal stones and will help urologists in choosing the technique

Comparison of simultaneous and sequential punctures while performing percutaneous nephrolithotomy for complex renal calculi - NIL

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2026/02/103055

Enrollment

Registered

2026-02-05

Start date

Unknown

Completion date

Unknown

Last updated

2026-03-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: N200- Calculus of kidney Health Condition 2: N200- Calculus of kidney

Interventions

Intervention1: Sequential Multi tract percutaneous nephrolithotomy: The multitract pcnl punctures will done one after another, as and when required. Intervention2: Simultaneous multi tract percutaneou

Eligibility

Inclusion criteria

Inclusion criteria: Patients with complex renal calculi undergoing PCNL, where complex renal calculi are renal calculi with STONE score 9 to 13

Exclusion criteria

Exclusion criteria: Patients where multiple punctures are not possible because of any reason (eg. Very less space between kidney and other viscera, malrotated or ectopic kidneys, limiting the access to calyces) Patients with active untreated urinary tract infection (UTI): Positive preoperative urine culture not adequately treated before surgery. Uncorrected coagulopathy: INR more than 1.5, platelet count less than 100,000 per mm despite correction. Pregnancy Patients on dialysis or with end-stage renal disease (eGFR less than 30 mLper min per 1.73 m )

Design outcomes

Primary

Measure	Time frame
Stone free rates at 48 hrs and 1 month Total initial punctures and actual tracts made Total fluoroscopy time and operative time Change in haematocrit pre and post surgery Complications as per Clavien-Dindo classification length of hospital stay (days) S.T.O.N.E. score, pre operatively and 1 month post operatively (in patients with residual stones)Timepoint: Intra op 6 hours post op 48 hours post op At the time of discharge 1 month	—

Measure

Time frame

Stone free rates at 48 hrs and 1 month Total initial punctures and actual tracts made Total fluoroscopy time and operative time Change in haematocrit pre and post surgery Complications as per Clavien-Dindo classification length of hospital stay (days) S.T.O.N.E. score, pre operatively and 1 month post operatively (in patients with residual stones)Timepoint: Intra op 6 hours post op 48 hours post op At the time of discharge 1 month

—

Secondary

Measure	Time frame
Number of additional procedures, if requiredTimepoint: Immediately post op	—

Countries

India

Contacts

Public ContactDr Neel Swaminarayan

Dr Babasaheb Ambedkar Medical college and Hospital

kartikurology85@gmail.com98183 77393

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Mar 14, 2026