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Ulcer size reduction and improvement in quality of life in venous ulcers treated with Collagen based dressing , Platelet rich Fibrin dressing , or no dressing combined with standard four layer compression bandages : a randomized control study

Ulcer size reduction and improvement in quality of life in venous ulcers treated with Collagen based dressing , Platelet rich Fibrin dressing , or no dressing combined with standard four layer compression bandages : a randomized control study. - NIL

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2026/02/103039
Enrollment
120
Registered
2026-02-04
Start date
Unknown
Completion date
Unknown
Last updated
2026-03-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: I830- Varicose veins of lower extremities with ulcer

Interventions

Intervention1: Collagen Based dressing: Collagen based dressing as an adjunct to standard 4 layer compression bandages Intervention2: Platelet rich fibrin: Platelet rich fibrin as an adjunct to standa

Sponsors

King George Medical University
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1. Chronic venous ulcer of lower extremity having for more than 3 months duration 2. Age more than 18 years

Exclusion criteria

Exclusion criteria: 1. Less than 3 months duration 2. Other causes like arterial/neuropathic/diabetic/vasculitis 3. Patients with Infected ulcers, osteomyelitis affecting the area of the ulcer, ulcers with exposed tendons or bones 4. Patients receiving antiplatelet drugs, anticoagulants, bleeding diathesis. 5. Patients not giving consent for being included in the study

Design outcomes

Primary

MeasureTime frame
Reduction in ulcer size over a span of 6 months measured by absolute reduction in ulcer size in cm2.Timepoint: Ulcer size to be measured at baseline,4,8,12,16,20 and 24 weeks—

Secondary

MeasureTime frame
Improvement in Quality of life: Measured by: Ulcer specific questionnaire: Charing Cross Venous Ulcer Questionnaire (CCVUQ) Disease specific questionnaire: The Chronic Venous Insufficiency Questionnaire (CIVIQ 20) Overall Quality of life questionnaire: World Health Organization Quality of Life BREF(WHOQOL-BREF) questionnaire Timepoint: 4 weeks , 8 weeks , 12 weeks , 16 weeks , 20 weeks , 24 weeks .—

Countries

India

Contacts

Public ContactDr Prateek Motiyani

Department of General Surgery , King George Medical University

drjkkushwaha@gmail.com9935345852

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Mar 14, 2026