Health Condition 1: H36- Retinal disorders in diseases classified elsewhere
Conditions
Interventions
Intervention1: Nil: Nil
Sponsors
Dr Shroffs Charity Eye Hospital, New Delhi
Eligibility
Inclusion criteria
Inclusion criteria: 1. Type 2 diabetic patients with or without clinically diagnosed DR. 2. Non-diabetic control subjects of similar age for baseline OCTA biomarker comparisons. 3. Clear ocular media allowing high-quality OCTA imaging. 4. Informed consent to participate in the study
Exclusion criteria
Exclusion criteria: 1. Retinal diseases such as age-related macular degeneration AMD, retinitis pigmentosa RP, retinal vein occlusion RVO, or central serous retinopathy CSR. 2. Recent intraocular surgeries less than 6 months or trauma. 3. Ocular media opacities like dense cataracts causing poor imaging quality.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Establishment of OCTA biomarker thresholds predictive of early diabetic retinopathy (DR). Measurement: Quantitative analysis of vessel density, foveal avascular zone (FAZ) area, and perfusion density using OCTA. Timepoint: Single assessment at baseline. | — |
Secondary
| Measure | Time frame |
|---|---|
| Correlation of OCTA biomarkers with systemic and visual parameters, including HbA1c, best-corrected visual acuity (BCVA), Contrast, and duration of diabetes. Comparison of the diagnostic accuracy of OCTA with fundus photography and fluorescein angiography (FA). Timepoint: Single assessment at baseline. | — |
Countries
India
Contacts
Public ContactDr Partha Chowdhury
Galgotias University
Outcome results
None listed