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A study comparing lidocaine and dexmedetomidine given as nebulisation to reduce changes in heart rate and blood pressure while putting the breathing tube into the windpipe .

A comparison of nebulised lidocaine versus dexmedetomidine for attenuation of hemodynamic response to laryngoscopy and tracheal intubation. - NIL

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2026/02/102959
Enrollment
60
Registered
2026-02-04
Start date
Unknown
Completion date
Unknown
Last updated
2026-03-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical

Interventions

Intervention1: Nebulisation of Lidocaine for attenuation of hemodynamic response to laryngoscopy and tracheal intubation: Administration of nebulised Lidocaine(2%)in doses of 2mg/kg 15 mins prior to a

Sponsors

BJ medical college and Civil hospital Ahmedabad
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Patients of ASA 1,2,3 undergoing any surgery under general anaesthesia requiring endotracheal intubation Patients with normal airway anatomy Non smokers

Exclusion criteria

Exclusion criteria: Patients with allergy to study medications Patients with pregnancy and lactation Patients with BMI more than 30 ASA 4,5 Patients who will give negative consent

Design outcomes

Primary

MeasureTime frame
To compare hemodynamic parameters before, during and after laryngoscopy in patients receiving lidocaine nebulisation versus those receiving dexmedetomidine nebulisationTimepoint: Before and after nebulisation,after pre-medication, before induction, at the time of laryngoscopy, at time of Intubation, on 1st,3rd,5th,10th, 30th minute, 1 hour, 2 hour after laryngoscopy and endotracheal intubation.—

Secondary

MeasureTime frame
To study and compare any adverse effect of lidocaine and dexmedetomidine. Timepoint: Till the completion of the surgery—

Countries

India

Contacts

Public ContactDr Siddharthkumar B Parmar

BJ Medical College, Ahmedabad.

drsid25@gmail.com9426332701

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Mar 14, 2026