How light-based dental treatment affects gum health, blood sugar control, and inflammation in people with type 2 diabetes who have gum disease.

Effects of photodynamic therapy on periodontal parameters and levels of HbA1c and hs-CRP in periodontitis patients with type 2 diabetes mellitus. - NIL

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2026/02/102945

Enrollment

Registered

2026-02-04

Start date

Unknown

Completion date

Unknown

Last updated

2026-03-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K051- Chronic gingivitis

Interventions

Intervention1: Photodynamic therapy: Photodynamic therapy using Diode laser at 970 nm using methylene blue dye Control Intervention1: Scalling and Root planing: Ultrasonic scaling using scalers ad the

Eligibility

Inclusion criteria

Inclusion criteria: 1. Patients with type 2 diabetes mellitus. 2. Patients having generalised periodontitis. 3. Patients with periodontal probing depths >=5mm and (CAL)Clinical attachment loss >= 3mm. 4. Patients aged 30-60 years of age. 5. Established willingness and ability to perform oral hygiene. 6. HbA1c levels >= 5.8% and

Exclusion criteria

Exclusion criteria: i. Systemic conditions that potentially affect periodontal health but are not related to diabetes. ii. Cigarette smoking iii. Past three months of antibiotic, anti-inflammatory, or periodontal treatment history. iv. Notable modifications to the management of diabetes mellitus over the study period.

Design outcomes

Primary

Measure	Time frame
1.To observe and correlate the clinical parameters, HbA1c and hs-CRP levels before and after treatment of Periodontitis in type 2 diabetes mellitus patients by SRP alone. 2.To observe and correlate the clinical parameters, HbA1c and hs-CRP levels before and after treatment of Periodontitis in type 2 diabetes mellitus patients by SRP along with Laser assisted photodynamic therapy. 3. To compare both the modalities for the treatment of periodontitis and their effects on levels of HbA1c and hs-CRP in periodontitis patients with type 2 diabetes mellitus. Timepoint: At Baseline 3 months 6 months	—

Measure

Time frame

1.To observe and correlate the clinical parameters, HbA1c and hs-CRP levels before and after treatment of Periodontitis in type 2 diabetes mellitus patients by SRP alone. 2.To observe and correlate the clinical parameters, HbA1c and hs-CRP levels before and after treatment of Periodontitis in type 2 diabetes mellitus patients by SRP along with Laser assisted photodynamic therapy. 3. To compare both the modalities for the treatment of periodontitis and their effects on levels of HbA1c and hs-CRP in periodontitis patients with type 2 diabetes mellitus. Timepoint: At Baseline 3 months 6 months

—

Secondary

Measure	Time frame
1. To observe clinical parameters and severity of periodontitis at various levels of HbA1c. 2. To observe clinical response to treatment of periodontitis in patients of type 2 diabetes mellitus. Timepoint: At Baseline 3 months 6 months	—

Countries

India

Contacts

Public ContactDrRiddhi Verma

Sardar Patel Post Graduate Institute Of Dental and Medical Sciences

docamitabh74@gmail.com9415085343

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Mar 14, 2026