Health Condition 1: D- Radiation Therapy
Conditions
Interventions
Intervention1: Nil: Nil
Intervention2: Nil: Nil
Sponsors
Maastricht Radiation Oncology Maastro Clinic
Eligibility
Inclusion criteria
Inclusion criteria: Rectal cancer patients who have been treated with rectal high dose rate brachytherapy at participating centers. Availability of complete treatment planning data including dose volume histogram information. Treatment plans generated using clinically approved treatment planning systems. Cases where target and relevant structures are delineated according to the specified delineation guideline or can be updated accordingly.
Exclusion criteria
Exclusion criteria: Cases with incomplete or missing treatment planning or dose volume histogram data. Treatment plans not suitable for dose volume histogram analysis due to technical limitations. Cases where required delineation structures are unavailable and cannot be reconstructed or updated.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Identification of robust dose volume and depth dose metrics for rectal high dose rate brachytherapy that are sensitive to clinically relevant variations in dose distribution and remain stable across contouring variability and treatment planning system differencesTimepoint: Not applicable | — |
Secondary
| Measure | Time frame |
|---|---|
| To evaluate inter-centre variability in contemporary clinical practice; assess the sensitivity of dosimetric outcomes to unavoidable target delineation uncertainties; examine susceptibility to variations in DVH calculation methods, treatment planning system software, & minor source positional deviations; & determine the feasibility of categorizing robust dosimetric metrics into entry-level, advanced-level, & research-level dose reporting frameworksTimepoint: Not applicable | — |
Countries
India
Contacts
Public ContactRahul Krishnatry
Tata Memorial
Outcome results
None listed